This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Lipase 3D Structures
From Proteopedia
(Difference between revisions)
| Line 21: | Line 21: | ||
*Prokaryote lipase: | *Prokaryote lipase: | ||
| - | **[[1llf]] – Lip – ''Candida cylindracea''<br /> | + | **[[1lpm]], [[1lps]] – CrLip closed state – ''Candida rugosa'' <br /> |
| + | **[[1crl]], [[1trh]] – CrLip open state<br /> | ||
| + | *[[1llf]] – Lip – ''Candida cylindracea''<br /> | ||
**[[3g7n]] – Lip - ''Penicillium expansum''<br /> | **[[3g7n]] – Lip - ''Penicillium expansum''<br /> | ||
**[[1tia]] - Lip – ''Penicillium camemberti''<br /> | **[[1tia]] - Lip – ''Penicillium camemberti''<br /> | ||
| Line 60: | Line 62: | ||
**[[5ah0]] – Lip – ''Pelosinus fermentans''<br /> | **[[5ah0]] – Lip – ''Pelosinus fermentans''<br /> | ||
**[[5ah1]] – Lip – ''Clostridium botulinum''<br /> | **[[5ah1]] – Lip – ''Clostridium botulinum''<br /> | ||
| - | **[[6khm]] – | + | **[[6khm]] – CuaLip open form – ''Cutibacterium acnes''<br /> |
| + | **[[6khk]], [[6khl]] – CuaLip closed form <br /> | ||
| + | **[[6nkc]], [[6nkd]], [[6nkf]], [[6nkg]] – Lip – goat metagenome<br /> | ||
| + | **[[7q4h]] – TtLip – Thermoanaerobacter thermohydrosulfuricus<br /> | ||
| + | |||
*Bacterial lipase A | *Bacterial lipase A | ||
| Line 71: | Line 77: | ||
**[[1r4z]] – BsLipA+Rc-IPG-phosphonate<br /> | **[[1r4z]] – BsLipA+Rc-IPG-phosphonate<br /> | ||
**[[1r50]] – BsLipA +Sc-IPG-phosphonate<br /> | **[[1r50]] – BsLipA +Sc-IPG-phosphonate<br /> | ||
| + | **[[7r1k]], [[7r25]] – LipA – ''Bacillus pumilus''<br /> | ||
*Bacterial lipase B | *Bacterial lipase B | ||
| Line 77: | Line 84: | ||
**[[3icv]], [[4k5q]], [[5k6h]], [[5k6k]] – CaLipB (mutant) <br /> | **[[3icv]], [[4k5q]], [[5k6h]], [[5k6k]] – CaLipB (mutant) <br /> | ||
**[[5gv5]] - CaLipB + phosphonate<br /> | **[[5gv5]] - CaLipB + phosphonate<br /> | ||
| + | **[[4k6h]] – CaLipB (mutant) <br /> | ||
**[[3icw]] – CaLipB (mutant) + phosphonate<br /> | **[[3icw]] – CaLipB (mutant) + phosphonate<br /> | ||
**[[5x7k]] – SmLipB NBD <br /> | **[[5x7k]] – SmLipB NBD <br /> | ||
| Line 84: | Line 92: | ||
**[[6idy]] - AfLipB - ''Aspergillus fumigatus''<br /> | **[[6idy]] - AfLipB - ''Aspergillus fumigatus''<br /> | ||
**[[7v6d]] - LipB - ''Lasiodiplodia theobromae''<br /> | **[[7v6d]] - LipB - ''Lasiodiplodia theobromae''<br /> | ||
| + | **[[7wol]] - LipB - ''Thermomicrobium roseum''<br /> | ||
*Bacterial lipase C | *Bacterial lipase C | ||
| Line 100: | Line 109: | ||
**[[1evq]] – AaEst2(LIPE) – ''Alicyclobacillus acidocaldarius''<br /> | **[[1evq]] – AaEst2(LIPE) – ''Alicyclobacillus acidocaldarius''<br /> | ||
**[[1u4n]] – AaEst2(LIPE) (mutant) <br /> | **[[1u4n]] – AaEst2(LIPE) (mutant) <br /> | ||
| - | **[[6keu]], [[7ci0]], [[7cip]] – ElEstE53(HSL) – ''Erythrobacter longus''<br /> | + | **[[6keu]], [[7ci0]], [[7cip]], [[7w8n]] – ElEstE53(HSL) – ''Erythrobacter longus''<br /> |
**[[6kf1]], [[6kf5]], [[6kf7]], [[7cih]] – ElEstE53(HSL) (mutant)<br /> | **[[6kf1]], [[6kf5]], [[6kf7]], [[7cih]] – ElEstE53(HSL) (mutant)<br /> | ||
| - | |||
| - | *Putative lipases; Proteins with unknown function but structural similarity to lipase obtained in structural genomics projects. | ||
| - | |||
| - | **[[2rau]] - Lip – ''Sulfolobus solfataricus''<br /> | ||
| - | **[[3bxp]], [[3d3n]] - Lip – ''Lactobacillus plantarum''<br /> | ||
| - | **[[3e0x]] - Lip – ''Clostridium acetobutylicum''<br /> | ||
| - | **[[1z8h]] – Lip – ''Nostoc sp.'' PCC 712<br /> | ||
| - | **[[1vj3]] - Lip – ''Nostoc sp.'' <br /> | ||
| - | **[[3bzw]] – Lip - ''Bacteroides thetaiotaomicron''<br /> | ||
| - | **[[2pbl]] – Lip - ''Silicibacter'' | ||
*Lipase + inhibitors | *Lipase + inhibitors | ||
| Line 135: | Line 134: | ||
**[[4n8s]] - TlLip + nitrobenzaldehyde + ethylacetoacetate<br /> | **[[4n8s]] - TlLip + nitrobenzaldehyde + ethylacetoacetate<br /> | ||
**[[4s0x]] – TlLip + lauric acid<br /> | **[[4s0x]] – TlLip + lauric acid<br /> | ||
| + | **[[4gxn]] – PmLip + inhibitor<br /> | ||
*Lipase conjugated with analogs to its reaction intermediates | *Lipase conjugated with analogs to its reaction intermediates | ||
| + | **[[1lpn]] – CrLip+ dodecanesulfonate <br /> | ||
| + | **[[1lpo]], [[1lpp]] – CrLip+ hexadecanesulfonate<br /> | ||
| + | **[[3rar]] – CrLip + phosphonate derivative<br /> | ||
**[[1qz3]] – EaEst2(mutant) (LIPE)+hexadecanesulfonate <br /> | **[[1qz3]] – EaEst2(mutant) (LIPE)+hexadecanesulfonate <br /> | ||
| Line 149: | Line 152: | ||
**[[3hju]], [[3jw8]], [[7ots]] - hMAGL <BR /> | **[[3hju]], [[3jw8]], [[7ots]] - hMAGL <BR /> | ||
| - | **[[3jwe]], [[3pe6]], [[4uuq]], [[6ax1]], [[6bq0]], [[7l4t]], [[7l4u]], [[7l4w]], [[7l50]] – hMAGL + inhibitor<br /> | + | **[[3jwe]], [[3pe6]], [[4uuq]], [[6ax1]], [[6bq0]], [[7l4t]], [[7l4u]], [[7l4w]], [[7l50]], [[7prm]], [[7zpg]] – hMAGL + inhibitor<br /> |
**[[4uuq]] - hMAGLip + SAR <br /> | **[[4uuq]] - hMAGLip + SAR <br /> | ||
**[[5zun]] – hMAGL (mutant) + inhibitor<br /> | **[[5zun]] – hMAGL (mutant) + inhibitor<br /> | ||
| Line 162: | Line 165: | ||
**[[4ke7]], [[4ke8]], [[4ke9]] – BaMAGL + ligand<br /> | **[[4ke7]], [[4ke8]], [[4ke9]] – BaMAGL + ligand<br /> | ||
**[[4ke6]], [[4kea]] – BaMAGL (mutant) + ligand<br /> | **[[4ke6]], [[4kea]] – BaMAGL (mutant) + ligand<br /> | ||
| + | **[[7q4j]] – TtLip + monoacylglycerol intermediate<br /> | ||
| + | **[[7e04]] – Lip – ''Cytobacillus oceanisediminis''<br /> | ||
*Triacylglycerol lipase | *Triacylglycerol lipase | ||
| Line 207: | Line 212: | ||
**[[6oau]], [[6e7k]], [[6oaz]], [[6ob0]] – hLPL + GPIHBP1<br /> | **[[6oau]], [[6e7k]], [[6oaz]], [[6ob0]] – hLPL + GPIHBP1<br /> | ||
| - | **[[6u7m]] – bLPL – Cryo EM<br /> | + | **[[6u7m]], [[8erl]] – bLPL – Cryo EM<br /> |
}} | }} | ||
[[Category:Topic Page]] | [[Category:Topic Page]] | ||
Current revision
3D Structures of Lipase
Updated on 18-June-2023
