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5di3

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==Crystal structure of Arl13B in complex with Arl3 of Chlamydomonas reinhardtii==
==Crystal structure of Arl13B in complex with Arl3 of Chlamydomonas reinhardtii==
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<StructureSection load='5di3' size='340' side='right' caption='[[5di3]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='5di3' size='340' side='right'caption='[[5di3]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5di3]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DI3 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DI3 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5di3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Chlamydomonas_reinhardtii Chlamydomonas reinhardtii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DI3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DI3 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5di3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5di3 OCA], [http://pdbe.org/5di3 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5di3 RCSB], [http://www.ebi.ac.uk/pdbsum/5di3 PDBsum]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GNP:PHOSPHOAMINOPHOSPHONIC+ACID-GUANYLATE+ESTER'>GNP</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5di3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5di3 OCA], [https://pdbe.org/5di3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5di3 RCSB], [https://www.ebi.ac.uk/pdbsum/5di3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5di3 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/ARL13_CHLRE ARL13_CHLRE]] Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B (By similarity). [[http://www.uniprot.org/uniprot/ARL3_CHLRE ARL3_CHLRE]] Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). Required for normal cytokinesis and cilia signaling. Required for targeting proteins to the ciliary membrane by releasing myristoylated protein from unc119 cargo adapters into the cilium.[UniProtKB:P36405]
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[https://www.uniprot.org/uniprot/ARL13_CHLRE ARL13_CHLRE] Cilium-specific protein required to control the microtubule-based, ciliary axoneme structure. May act by maintaining the association between IFT subcomplexes A and B (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Falk, N]]
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[[Category: Chlamydomonas reinhardtii]]
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[[Category: Giessl, A]]
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[[Category: Large Structures]]
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[[Category: Gotthardt, K]]
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[[Category: Falk N]]
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[[Category: Koerner, C]]
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[[Category: Giessl A]]
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[[Category: Lokaj, M]]
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[[Category: Gotthardt K]]
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[[Category: Wittinghofer, A]]
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[[Category: Koerner C]]
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[[Category: Adp ribosylation like protein]]
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[[Category: Lokaj M]]
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[[Category: Complex]]
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[[Category: Wittinghofer A]]
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[[Category: G-protein]]
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[[Category: Guanine nucleotide exchange factor]]
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[[Category: Hydrolase]]
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Current revision

Crystal structure of Arl13B in complex with Arl3 of Chlamydomonas reinhardtii

PDB ID 5di3

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