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5dir

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==membrane protein at 2.8 Angstroms==
==membrane protein at 2.8 Angstroms==
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<StructureSection load='5dir' size='340' side='right' caption='[[5dir]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
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<StructureSection load='5dir' size='340' side='right'caption='[[5dir]], [[Resolution|resolution]] 2.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5dir]] is a 4 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DIR OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DIR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5dir]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_PAO1 Pseudomonas aeruginosa PAO1] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DIR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DIR FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5BV:(2R,3R)-3-(GLYCYLOXY)-2-METHYLNONANOIC+ACID'>5BV</scene>, <scene name='pdbligand=ALO:ALLO-THREONINE'>ALO</scene>, <scene name='pdbligand=IIL:ISO-ISOLEUCINE'>IIL</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=SER:SERINE'>SER</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.8&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Signal_peptidase_II Signal peptidase II], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.36 3.4.23.36] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5BV:(2R,3R)-3-(GLYCYLOXY)-2-METHYLNONANOIC+ACID'>5BV</scene>, <scene name='pdbligand=ALO:ALLO-THREONINE'>ALO</scene>, <scene name='pdbligand=IIL:ISO-ISOLEUCINE'>IIL</scene>, <scene name='pdbligand=MLE:N-METHYLLEUCINE'>MLE</scene>, <scene name='pdbligand=OLC:(2R)-2,3-DIHYDROXYPROPYL+(9Z)-OCTADEC-9-ENOATE'>OLC</scene>, <scene name='pdbligand=PRD_002257:Globomycin'>PRD_002257</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5dir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dir OCA], [http://pdbe.org/5dir PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5dir RCSB], [http://www.ebi.ac.uk/pdbsum/5dir PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5dir FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5dir OCA], [https://pdbe.org/5dir PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5dir RCSB], [https://www.ebi.ac.uk/pdbsum/5dir PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5dir ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LSPA_PSEAE LSPA_PSEAE]] This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
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[https://www.uniprot.org/uniprot/LSPA_PSEAE LSPA_PSEAE] This protein specifically catalyzes the removal of signal peptides from prolipoproteins.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Signal peptidase II]]
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[[Category: Large Structures]]
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[[Category: Arnaout, T El]]
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[[Category: Pseudomonas aeruginosa PAO1]]
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[[Category: Bailey, J]]
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[[Category: Synthetic construct]]
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[[Category: Boland, C]]
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[[Category: Bailey J]]
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[[Category: Caffrey, M]]
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[[Category: Boland C]]
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[[Category: Vogeley, L]]
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[[Category: Caffrey M]]
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[[Category: Antibiotic]]
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[[Category: El Arnaout T]]
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[[Category: Complex]]
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[[Category: Vogeley L]]
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[[Category: Hydrolase]]
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[[Category: Membrane protein]]
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[[Category: Protease]]
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membrane protein at 2.8 Angstroms

PDB ID 5dir

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