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5drp

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==Structure of the AaLpxC/LPC-023 Complex==
==Structure of the AaLpxC/LPC-023 Complex==
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<StructureSection load='5drp' size='340' side='right' caption='[[5drp]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
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<StructureSection load='5drp' size='340' side='right'caption='[[5drp]], [[Resolution|resolution]] 1.89&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5drp]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Aquae Aquae]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DRP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5DRP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5drp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Aquifex_aeolicus_VF5 Aquifex aeolicus VF5]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5DRP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5DRP FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5EP:N~2~-{4-[4-(4-AMINOPHENYL)BUTA-1,3-DIYN-1-YL]BENZOYL}-N-HYDROXY-L-ISOLEUCINAMIDE'>5EP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.889&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5dro|5dro]], [[5drq|5drq]], [[5drr|5drr]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5EP:N~2~-{4-[4-(4-AMINOPHENYL)BUTA-1,3-DIYN-1-YL]BENZOYL}-N-HYDROXY-L-ISOLEUCINAMIDE'>5EP</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">lpxC, envA, aq_1772 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=224324 AQUAE])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5drp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5drp OCA], [https://pdbe.org/5drp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5drp RCSB], [https://www.ebi.ac.uk/pdbsum/5drp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5drp ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5drp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5drp OCA], [http://pdbe.org/5drp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5drp RCSB], [http://www.ebi.ac.uk/pdbsum/5drp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5drp ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LPXC_AQUAE LPXC_AQUAE]] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity).
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[https://www.uniprot.org/uniprot/LPXC_AQUAE LPXC_AQUAE] Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5drp" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5drp" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[UDP-3-O-acyl-N-acetylglucosamine deacetylase|UDP-3-O-acyl-N-acetylglucosamine deacetylase]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Aquae]]
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[[Category: Aquifex aeolicus VF5]]
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[[Category: Lee, C J]]
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[[Category: Large Structures]]
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[[Category: Najeeb, J]]
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[[Category: Lee C-J]]
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[[Category: Zhou, P]]
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[[Category: Najeeb J]]
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[[Category: Gram-negative bacteria]]
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[[Category: Zhou P]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Inhibitor]]
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[[Category: Lipid some]]
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[[Category: Lpxc]]
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Current revision

Structure of the AaLpxC/LPC-023 Complex

PDB ID 5drp

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