This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5e3k

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:11, 5 July 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==Crystal structure of the ornithine aminotransferase from Toxoplasma gondii ME49 in a complex with (S)-4-amino-5-fluoropentanoic acid==
==Crystal structure of the ornithine aminotransferase from Toxoplasma gondii ME49 in a complex with (S)-4-amino-5-fluoropentanoic acid==
-
<StructureSection load='5e3k' size='340' side='right' caption='[[5e3k]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
+
<StructureSection load='5e3k' size='340' side='right'caption='[[5e3k]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5e3k]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E3K OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5E3K FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5e3k]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Toxoplasma_gondii_ME49 Toxoplasma gondii ME49]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E3K OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5E3K FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5JV:4-[(E)-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYLIDENE)AMINO]PENT-4-ENOIC+ACID'>5JV</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5dj9|5dj9]], [[4zwm|4zwm]], [[4zlv|4zlv]], [[4nog|4nog]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5JV:4-[(E)-({3-HYDROXY-2-METHYL-5-[(PHOSPHONOOXY)METHYL]PYRIDIN-4-YL}METHYLIDENE)AMINO]PENT-4-ENOIC+ACID'>5JV</scene>, <scene name='pdbligand=CO3:CARBONATE+ION'>CO3</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Ornithine_aminotransferase Ornithine aminotransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.6.1.13 2.6.1.13] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5e3k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e3k OCA], [https://pdbe.org/5e3k PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5e3k RCSB], [https://www.ebi.ac.uk/pdbsum/5e3k PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5e3k ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5e3k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e3k OCA], [http://pdbe.org/5e3k PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e3k RCSB], [http://www.ebi.ac.uk/pdbsum/5e3k PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5e3k ProSAT]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/S8EY38_TOXGM S8EY38_TOXGM]
 +
 +
==See Also==
 +
*[[Aminotransferase 3D structures|Aminotransferase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Ornithine aminotransferase]]
+
[[Category: Large Structures]]
-
[[Category: Anderson, W F]]
+
[[Category: Toxoplasma gondii ME49]]
-
[[Category: Structural genomic]]
+
[[Category: Anderson WF]]
-
[[Category: Filippova, E V]]
+
[[Category: Filippova EV]]
-
[[Category: Flores, K]]
+
[[Category: Flores K]]
-
[[Category: Le, H V]]
+
[[Category: Le HV]]
-
[[Category: McLeod, R L]]
+
[[Category: McLeod RL]]
-
[[Category: Minasov, G]]
+
[[Category: Minasov G]]
-
[[Category: Silverman, R B]]
+
[[Category: Silverman RB]]
-
[[Category: Complex]]
+
-
[[Category: Csgid]]
+
-
[[Category: Inhibitor]]
+
-
[[Category: Parasite]]
+
-
[[Category: Pyridoxal 5'-phosphate]]
+
-
[[Category: Transferase]]
+

Current revision

Crystal structure of the ornithine aminotransferase from Toxoplasma gondii ME49 in a complex with (S)-4-amino-5-fluoropentanoic acid

PDB ID 5e3k

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools