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5e4g

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==Crystal structure of human growth differentiation factor 11 (GDF-11)==
==Crystal structure of human growth differentiation factor 11 (GDF-11)==
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<StructureSection load='5e4g' size='340' side='right' caption='[[5e4g]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
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<StructureSection load='5e4g' size='340' side='right'caption='[[5e4g]], [[Resolution|resolution]] 1.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5e4g]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E4G OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5E4G FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5e4g]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5E4G OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5E4G FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5e4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e4g OCA], [http://pdbe.org/5e4g PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5e4g RCSB], [http://www.ebi.ac.uk/pdbsum/5e4g PDBsum]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5e4g FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5e4g OCA], [https://pdbe.org/5e4g PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5e4g RCSB], [https://www.ebi.ac.uk/pdbsum/5e4g PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5e4g ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GDF11_HUMAN GDF11_HUMAN]] Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. Play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern.
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[https://www.uniprot.org/uniprot/GDF11_HUMAN GDF11_HUMAN] Secreted signal that acts globally to specify positional identity along the anterior/posterior axis during development. Play critical roles in patterning both mesodermal and neural tissues and in establishing the skeletal pattern.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5e4g" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5e4g" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Growth differentiation factor 3D STRUCTURES|Growth differentiation factor 3D STRUCTURES]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Farrow, N A]]
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[[Category: Homo sapiens]]
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[[Category: Franti, M]]
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[[Category: Large Structures]]
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[[Category: Gupta, P]]
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[[Category: Farrow NA]]
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[[Category: Hayes, D B]]
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[[Category: Franti M]]
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[[Category: Padyana, A K]]
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[[Category: Gupta P]]
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[[Category: Vaidialingam, B]]
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[[Category: Hayes DB]]
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[[Category: Bmp-11]]
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[[Category: Padyana AK]]
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[[Category: Bone morphogenetic protein 11]]
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[[Category: Vaidialingam B]]
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[[Category: Gdf 11]]
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[[Category: Growth factor]]
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[[Category: Hormone]]
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Current revision

Crystal structure of human growth differentiation factor 11 (GDF-11)

PDB ID 5e4g

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