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8a4d
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==1-deoxy-D-xylulose 5-phosphate synthase from Pseudomonas aeruginosa with thiamine analog inhibitor== | |
| - | + | <StructureSection load='8a4d' size='340' side='right'caption='[[8a4d]], [[Resolution|resolution]] 2.20Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8a4d]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa_LESB58 Pseudomonas aeruginosa LESB58]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8A4D OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8A4D FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=26G:2-{3-[(4-AMINO-2-METHYLPYRIMIDIN-5-YL)METHYL]PHENYL}ETHANOL'>26G</scene>, <scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr> |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8a4d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8a4d OCA], [https://pdbe.org/8a4d PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8a4d RCSB], [https://www.ebi.ac.uk/pdbsum/8a4d PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8a4d ProSAT]</span></td></tr> |
| - | [[Category: Hamid | + | </table> |
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/DXS_PSEA8 DXS_PSEA8] Catalyzes the acyloin condensation reaction between C atoms 2 and 3 of pyruvate and glyceraldehyde 3-phosphate to yield 1-deoxy-D-xylulose-5-phosphate (DXP). | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Pseudomonas aeruginosa LESB58]] | ||
| + | [[Category: Hamid R]] | ||
| + | [[Category: Hirsch A]] | ||
Current revision
1-deoxy-D-xylulose 5-phosphate synthase from Pseudomonas aeruginosa with thiamine analog inhibitor
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