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5eph

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==Crystal structure of extended-spectrum beta-lactamase BEL-1 in complex with Imipenem==
==Crystal structure of extended-spectrum beta-lactamase BEL-1 in complex with Imipenem==
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<StructureSection load='5eph' size='340' side='right' caption='[[5eph]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
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<StructureSection load='5eph' size='340' side='right'caption='[[5eph]], [[Resolution|resolution]] 1.79&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5eph]] is a 4 chain structure. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4mxb 4mxb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EPH OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EPH FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5eph]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=4mxb 4mxb]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EPH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EPH FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ID1:IMIPENEM'>ID1</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.79&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5eoo|5eoo]], [[5eoe|5eoe]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=ID1:IMIPENEM'>ID1</scene>, <scene name='pdbligand=MRD:(4R)-2-METHYLPENTANE-2,4-DIOL'>MRD</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5eph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eph OCA], [https://pdbe.org/5eph PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5eph RCSB], [https://www.ebi.ac.uk/pdbsum/5eph PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5eph ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5eph FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eph OCA], [http://pdbe.org/5eph PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eph RCSB], [http://www.ebi.ac.uk/pdbsum/5eph PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5eph ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q3SAW3_PSEAI Q3SAW3_PSEAI]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5eph" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5eph" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Beta-lactamase 3D structures|Beta-lactamase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Beta-lactamase]]
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[[Category: Large Structures]]
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[[Category: Benvenuti, M]]
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[[Category: Docquier, J D]]
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[[Category: Luca, F De]]
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[[Category: Mangani, S]]
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[[Category: Pozzi, C]]
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[[Category: Extended-spectrum beta-lactamase]]
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[[Category: Hydrolase-antibiotic complex]]
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[[Category: Pseudomonas aeruginosa]]
[[Category: Pseudomonas aeruginosa]]
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[[Category: Benvenuti M]]
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[[Category: De Luca F]]
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[[Category: Docquier JD]]
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[[Category: Mangani S]]
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[[Category: Pozzi C]]

Current revision

Crystal structure of extended-spectrum beta-lactamase BEL-1 in complex with Imipenem

PDB ID 5eph

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