This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5eu9

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (08:24, 12 July 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 3: Line 3:
<StructureSection load='5eu9' size='340' side='right'caption='[[5eu9]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
<StructureSection load='5eu9' size='340' side='right'caption='[[5eu9]], [[Resolution|resolution]] 2.05&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5eu9]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EU9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EU9 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5eu9]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EU9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EU9 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5TX:((3S,5S)-1,5-DIHYDROXY-3-METHYL-2-OXOPYRROLIDIN-3-YL)PHOSPHONIC+ACID'>5TX</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.047&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4zcw|4zcw]], [[4za0|4za0]], [[1te6|1te6]], [[2akm|2akm]], [[2akz|2akz]], [[3ucc|3ucc]], [[3ucd|3ucd]], [[3uje|3uje]], [[3ujf|3ujf]], [[3ujr|3ujr]], [[3ujs|3ujs]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5TX:((3S,5S)-1,5-DIHYDROXY-3-METHYL-2-OXOPYRROLIDIN-3-YL)PHOSPHONIC+ACID'>5TX</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">ENO2 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5eu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eu9 OCA], [https://pdbe.org/5eu9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5eu9 RCSB], [https://www.ebi.ac.uk/pdbsum/5eu9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5eu9 ProSAT]</span></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphopyruvate_hydratase Phosphopyruvate hydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.11 4.2.1.11] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5eu9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5eu9 OCA], [http://pdbe.org/5eu9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5eu9 RCSB], [http://www.ebi.ac.uk/pdbsum/5eu9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5eu9 ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/ENOG_HUMAN ENOG_HUMAN]] Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity).
+
[https://www.uniprot.org/uniprot/ENOG_HUMAN ENOG_HUMAN] Has neurotrophic and neuroprotective properties on a broad spectrum of central nervous system (CNS) neurons. Binds, in a calcium-dependent manner, to cultured neocortical neurons and promotes cell survival (By similarity).
==See Also==
==See Also==
-
*[[Enolase|Enolase]]
+
*[[Enolase 3D structures|Enolase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Human]]
+
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Phosphopyruvate hydratase]]
+
[[Category: Leonard PG]]
-
[[Category: Leonard, P G]]
+
[[Category: Muller FL]]
-
[[Category: Muller, F L]]
+
-
[[Category: Carbohydrate metabolism]]
+
-
[[Category: Enolase gamma]]
+
-
[[Category: Glycolysis]]
+
-
[[Category: Lyase-lyase inhibitor complex]]
+
-
[[Category: Neuron specific enolase]]
+

Current revision

Structure of Human Enolase 2 in complex with ((3S,5S)-1,5-dihydroxy-3-methyl-2-oxopyrrolidin-3-yl)phosphonic acid

PDB ID 5eu9

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools