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5ey8

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==Structure of FadD32 from Mycobacterium smegmatis complexed to AMPC20==
==Structure of FadD32 from Mycobacterium smegmatis complexed to AMPC20==
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<StructureSection load='5ey8' size='340' side='right' caption='[[5ey8]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
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<StructureSection load='5ey8' size='340' side='right'caption='[[5ey8]], [[Resolution|resolution]] 3.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ey8]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EY8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5EY8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ey8]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycolicibacterium_smegmatis Mycolicibacterium smegmatis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5EY8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5EY8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=5SV:[(2~{R},3~{S},4~{R},5~{R})-5-(6-AMINOPURIN-9-YL)-3,4-BIS(OXIDANYL)OXOLAN-2-YL]METHYL+ICOSYL+HYDROGEN+PHOSPHATE'>5SV</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ey8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ey8 OCA], [http://pdbe.org/5ey8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ey8 RCSB], [http://www.ebi.ac.uk/pdbsum/5ey8 PDBsum]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5SV:[(2~{R},3~{S},4~{R},5~{R})-5-(6-AMINOPURIN-9-YL)-3,4-BIS(OXIDANYL)OXOLAN-2-YL]METHYL+ICOSYL+HYDROGEN+PHOSPHATE'>5SV</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ey8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ey8 OCA], [https://pdbe.org/5ey8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ey8 RCSB], [https://www.ebi.ac.uk/pdbsum/5ey8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ey8 ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/FAA32_MYCS2 FAA32_MYCS2] Involved in the biosynthesis of mycolic acids (By similarity). Catalyzes the activation of long-chain fatty acids as acyl-adenylates (acyl-AMP), which are then transferred to the phosphopantetheine arm of the polyketide synthase Pks13 for further chain extension (By similarity). Can use decanoate (C10), dodecanoate (C12) and tetradecanoate (C14) (PubMed:23364516, PubMed:26900152).[UniProtKB:O53580]<ref>PMID:23364516</ref> <ref>PMID:26900152</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Guillet, V]]
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[[Category: Large Structures]]
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[[Category: Maveyraud, L]]
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[[Category: Mycolicibacterium smegmatis]]
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[[Category: Mourey, L]]
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[[Category: Guillet V]]
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[[Category: Fatty-acyl amp ligase]]
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[[Category: Maveyraud L]]
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[[Category: Ligase]]
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[[Category: Mourey L]]

Current revision

Structure of FadD32 from Mycobacterium smegmatis complexed to AMPC20

PDB ID 5ey8

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