Netrin receptor

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Line 32: Line 32:
**[[3laf]] – rDCC residues 39-421 - rat<BR />
**[[3laf]] – rDCC residues 39-421 - rat<BR />
**[[5z5k]] – rDCC residues 39-421 + draxin peptide <BR />
**[[5z5k]] – rDCC residues 39-421 + draxin peptide <BR />
 +
 +
*Netrin receptor UNC5
 +
 +
**[[8edc]] – `CeUNC5D Ig1+Ig2 domains 29-228 – ''Caenorhabditis elegans''<BR />
 +
**[[8edi]] – `CeUNC5D Ig1+Ig2 domains + heparin<BR />
*Netrin receptor UNC5A
*Netrin receptor UNC5A
Line 46: Line 51:
**[[4v2b]] – rUNC5D Ig1 domain <BR />
**[[4v2b]] – rUNC5D Ig1 domain <BR />
**[[4v2c]] – rUNC5D Ig1 domain + FLRT2 LRR domain<BR />
**[[4v2c]] – rUNC5D Ig1 domain + FLRT2 LRR domain<BR />
 +
**[[7za1]], [[7za2]], [[7za3]] – rUNC5D residues 46-307 + glypican-3<BR />
**[[5ftt]], [[5ftu]] – mUNC5D Ig1, Ig2, TSP1 domains + FLRT2 LRR domain + latrophilin 3<BR />
**[[5ftt]], [[5ftu]] – mUNC5D Ig1, Ig2, TSP1 domains + FLRT2 LRR domain + latrophilin 3<BR />

Revision as of 07:02, 13 July 2023

Glycosylated human netrin receptor DCC fibronectin type V-VI domains (green) complex with neutrin-1 (grey), sulfate, Ca+2 and Cl-1 ions (PDB code 4urt)

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3D Structures of netrin receptor

Updated on 13-July-2023

References

  1. Moore SW, Tessier-Lavigne M, Kennedy TE. Netrins and their receptors. Adv Exp Med Biol. 2007;621:17-31. doi: 10.1007/978-0-387-76715-4_2. PMID:18269208 doi:http://dx.doi.org/10.1007/978-0-387-76715-4_2
  2. Mehlen P, Llambi F. Role of netrin-1 and netrin-1 dependence receptors in colorectal cancers. Br J Cancer. 2005 Jul 11;93(1):1-6. PMID:15956977 doi:http://dx.doi.org/10.1038/sj.bjc.6602656

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Michal Harel

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