Neuropilin

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Current revision (06:21, 16 July 2023) (edit) (undo)
 
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{{#tree:id=OrganizedByTopic|openlevels=0|
{{#tree:id=OrganizedByTopic|openlevels=0|
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*NRP-1
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*NRP-1; Domains - B1 273-427, MAM 628-813, A2B1B2 141-586
**[[1kex]], [[2qqi]] – hNRP-1 B1 domain – human<br />
**[[1kex]], [[2qqi]] – hNRP-1 B1 domain – human<br />
**[[4rn5]] – hNRP-1 B1 domain<br />
**[[4rn5]] – hNRP-1 B1 domain<br />
 +
**[[7o1n]] – hNRP-1 B1 domain (mutant)<br />
**[[5l73]] – hNRP-1 MAM domain<br />
**[[5l73]] – hNRP-1 MAM domain<br />
**[[2qqm]] - hNRP-1 A2+B1+B2 domains<br />
**[[2qqm]] - hNRP-1 A2+B1+B2 domains<br />
**[[4deq]] - hNRP-1 B1 domain + VEGF-A heparin-binding domain<br />
**[[4deq]] - hNRP-1 B1 domain + VEGF-A heparin-binding domain<br />
**[[6tkk]] - hNRP-1 B1 domain + VEGF-A peptide<br />
**[[6tkk]] - hNRP-1 B1 domain + VEGF-A peptide<br />
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**[[7jcc]] - hNRP-1 B1 domain + SARS-CoV-2 peptide<br />
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**[[7p5u]] - hNRP-1 B1 domain + VEGF-B peptide<br />
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**[[7jjc]] - hNRP-1 B1 domain + SARS-CoV-2 peptide<br />
**[[2qqn]] - hNRP-1 B1 domain + VEGF-blocking antibody
**[[2qqn]] - hNRP-1 B1 domain + VEGF-blocking antibody
**[[5c7g]] – hNRP-1 B1 domain + bicine<br />
**[[5c7g]] – hNRP-1 B1 domain + bicine<br />
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*NRP-2; Domains - CUB 27-145; A2 145-275; B1 275-430; B2 431-595
*NRP-2; Domains - CUB 27-145; A2 145-275; B1 275-430; B2 431-595
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**[[7t4s]] – hNRP-2 + Herpes virus envelope + antibody – Cryo EM<br />
**[[4qdq]], [[4qds]], [[2qqj]] - hNRP-2 B1+B2 domains<br />
**[[4qdq]], [[4qds]], [[2qqj]] - hNRP-2 B1+B2 domains<br />
**[[5dq0]] – hNRP-2 B1 domain<br />
**[[5dq0]] – hNRP-2 B1 domain<br />

Current revision

Human glycosylated neuropilin-1 domains A2,B1,B2 complex with ethylene glycol and Ca+2 ion (green) 2qqm

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3D Structures of Neuropilin

Updated on 16-July-2023

References

  1. Romeo PH, Lemarchandel V, Tordjman R. Neuropilin-1 in the immune system. Adv Exp Med Biol. 2002;515:49-54. PMID:12613542
  2. Pellet-Many C, Frankel P, Jia H, Zachary I. Neuropilins: structure, function and role in disease. Biochem J. 2008 Apr 15;411(2):211-26. doi: 10.1042/BJ20071639. PMID:18363553 doi:http://dx.doi.org/10.1042/BJ20071639

Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Alexander Berchansky, Joel L. Sussman

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