Neutrophil gelatinase-associated lipocalin

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*Neutrophil gelatinase-associated lipocalin
*Neutrophil gelatinase-associated lipocalin
-
**[[1dfv]], [[1qqs]], [[3bx8]], [[6gqz]] – hNGAL – human <br />
+
**[[1dfv]], [[1qqs]], [[3bx8]], [[6gqz]], [[6z6z]] – hNGAL – human <br />
**[[3dtq]], [[5jr8]], [[5mhh]], [[6o5d]], [[6qmu]] – hNGAL (mutant)<br />
**[[3dtq]], [[5jr8]], [[5mhh]], [[6o5d]], [[6qmu]] – hNGAL (mutant)<br />
**[[1ngl]] – hNGAL - NMR<br />
**[[1ngl]] – hNGAL - NMR<br />
Line 51: Line 51:
**[[4qae]] – hNGAL (mutant) + hepcidin<br />
**[[4qae]] – hNGAL (mutant) + hepcidin<br />
**[[3bx7]] – hNGAL + CTLA-4<br />
**[[3bx7]] – hNGAL + CTLA-4<br />
 +
**[[6z2c]] – hNGAL + transition state analog<br />
**[[4mvi]], [[4mvk]], [[4mvl]] – hNGAL (mutant) + beta-APP40<br />
**[[4mvi]], [[4mvk]], [[4mvl]] – hNGAL (mutant) + beta-APP40<br />
**[[6s8v]] – hNGAL + h4F2HC<br />
**[[6s8v]] – hNGAL + h4F2HC<br />

Current revision

Structure of human neutrophil gelatinase-associated lipocalin complex with Fe+3 ion and Siderophores (PDB code 1x71).

Drag the structure with the mouse to rotate

3D structures of neutrophil gelatinase-associated lipocalin

Updated on 16-July-2023

References

  1. Friedl A, Stoesz SP, Buckley P, Gould MN. Neutrophil gelatinase-associated lipocalin in normal and neoplastic human tissues. Cell type-specific pattern of expression. Histochem J. 1999 Jul;31(7):433-41. PMID:10475571
  2. Dartt DA. Tear lipocalin: structure and function. Ocul Surf. 2011 Jul;9(3):126-38. PMID:21791187
  3. Viau A, El Karoui K, Laouari D, Burtin M, Nguyen C, Mori K, Pillebout E, Berger T, Mak TW, Knebelmann B, Friedlander G, Barasch J, Terzi F. Lipocalin 2 is essential for chronic kidney disease progression in mice and humans. J Clin Invest. 2010 Nov;120(11):4065-76. doi: 10.1172/JCI42004. PMID:20921623 doi:http://dx.doi.org/10.1172/JCI42004
  4. Holmes MA, Paulsene W, Jide X, Ratledge C, Strong RK. Siderocalin (Lcn 2) also binds carboxymycobactins, potentially defending against mycobacterial infections through iron sequestration. Structure. 2005 Jan;13(1):29-41. PMID:15642259 doi:10.1016/j.str.2004.10.009

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Michal Harel, Alexander Berchansky, Joel L. Sussman

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