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8guv

From Proteopedia

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Current revision (06:14, 19 July 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8guv is ON HOLD until Paper Publication
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==LecA from Pseudomonas aeruginosa in complex with tolcapone (CAS: 134308-13-7)==
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<StructureSection load='8guv' size='340' side='right'caption='[[8guv]], [[Resolution|resolution]] 1.32&Aring;' scene=''>
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Authors: Kuhaudomlarp, S., Siebs, E., Varrot, A., Imberty, A., Titz, A.
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8guv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8GUV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8GUV FirstGlance]. <br>
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Description: LecA from Pseudomonas aeruginosa in complex with tolcapone (CAS: 134308-13-7)
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.32&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=TCW:TOLCAPONE'>TCW</scene></td></tr>
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[[Category: Siebs, E]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8guv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8guv OCA], [https://pdbe.org/8guv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8guv RCSB], [https://www.ebi.ac.uk/pdbsum/8guv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8guv ProSAT]</span></td></tr>
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[[Category: Kuhaudomlarp, S]]
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</table>
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[[Category: Varrot, A]]
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== Function ==
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[[Category: Titz, A]]
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[https://www.uniprot.org/uniprot/PA1L_PSEAE PA1L_PSEAE] D-galactose specific lectin. Binds in decreasing order of affinity: melibiose, methyl-alpha-D-galactoside, D-galactose, methyl-beta-D-galactoside, N-acetyl-D-galactosamine. Similar to plant lectins in its selective (carbohydrate-specific) hemagglutinating activity.
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[[Category: Imberty, A]]
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
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[[Category: Pseudomonas aeruginosa]]
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[[Category: Imberty A]]
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[[Category: Kuhaudomlarp S]]
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[[Category: Siebs E]]
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[[Category: Titz A]]
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[[Category: Varrot A]]

Current revision

LecA from Pseudomonas aeruginosa in complex with tolcapone (CAS: 134308-13-7)

PDB ID 8guv

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