7z4s
From Proteopedia
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of SARS-CoV-2 Mpro in complex with cyclic peptide GM4 including unnatural amino acids.== | |
| - | + | <StructureSection load='7z4s' size='340' side='right'caption='[[7z4s]], [[Resolution|resolution]] 1.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7z4s]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Severe_acute_respiratory_syndrome_coronavirus_2 Severe acute respiratory syndrome coronavirus 2] and [https://en.wikipedia.org/wiki/Synthetic_construct Synthetic construct]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7Z4S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7Z4S FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AEA:(2-AMINO-2-CARBAMOYL-ETHYLSULFANYL)-ACETIC+ACID'>AEA</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=DTY:D-TYROSINE'>DTY</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=II7:3-azanylcyclobutane-1-carbaldehyde'>II7</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7z4s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7z4s OCA], [https://pdbe.org/7z4s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7z4s RCSB], [https://www.ebi.ac.uk/pdbsum/7z4s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7z4s ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A0A7L7QTZ6_SARS2 A0A7L7QTZ6_SARS2] | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Severe acute respiratory syndrome coronavirus 2]] | ||
| + | [[Category: Synthetic construct]] | ||
| + | [[Category: Brewitz L]] | ||
| + | [[Category: Katoh T]] | ||
| + | [[Category: Kawamura A]] | ||
| + | [[Category: Lukacik L]] | ||
| + | [[Category: Malla T]] | ||
| + | [[Category: McDonough MA]] | ||
| + | [[Category: Miura T]] | ||
| + | [[Category: Owen CD]] | ||
| + | [[Category: Salah E]] | ||
| + | [[Category: Schofield CJ]] | ||
| + | [[Category: Strain-Damerell CM]] | ||
| + | [[Category: Suga H]] | ||
| + | [[Category: Terasaka N]] | ||
| + | [[Category: Tumber A]] | ||
| + | [[Category: Walsh MA]] | ||
Current revision
Crystal structure of SARS-CoV-2 Mpro in complex with cyclic peptide GM4 including unnatural amino acids.
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