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3kbx

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[[Image:3kbx.png|left|200px]]
 
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==Human macrophage inflammatory protein-1 alpha L3M_V63M==
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The line below this paragraph, containing "STRUCTURE_3kbx", creates the "Structure Box" on the page.
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<StructureSection load='3kbx' size='340' side='right'caption='[[3kbx]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[3kbx]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KBX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KBX FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.652&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=K:POTASSIUM+ION'>K</scene>, <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr>
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{{STRUCTURE_3kbx| PDB=3kbx | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3kbx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3kbx OCA], [https://pdbe.org/3kbx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3kbx RCSB], [https://www.ebi.ac.uk/pdbsum/3kbx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3kbx ProSAT]</span></td></tr>
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</table>
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===Human macrophage inflammatory protein-1 alpha L3M_V63M===
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== Function ==
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[https://www.uniprot.org/uniprot/CCL3_HUMAN CCL3_HUMAN] Monokine with inflammatory and chemokinetic properties. Binds to CCR1, CCR4 and CCR5. One of the major HIV-suppressive factors produced by CD8+ T-cells. Recombinant MIP-1-alpha induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV).<ref>PMID:8525373</ref>
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== References ==
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==About this Structure==
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<references/>
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[[3kbx]] is a 5 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KBX OCA].
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Guo, Q.]]
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[[Category: Large Structures]]
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[[Category: Ren, M.]]
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[[Category: Guo Q]]
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[[Category: Tang, W J.]]
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[[Category: Ren M]]
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[[Category: Chemokine]]
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[[Category: Tang W-J]]
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[[Category: Chemotaxis]]
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[[Category: Cytokine]]
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[[Category: Inflammatory response]]
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[[Category: Secreted]]
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Current revision

Human macrophage inflammatory protein-1 alpha L3M_V63M

PDB ID 3kbx

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