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3knr

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<StructureSection load='3knr' size='340' side='right'caption='[[3knr]], [[Resolution|resolution]] 1.71&Aring;' scene=''>
<StructureSection load='3knr' size='340' side='right'caption='[[3knr]], [[Resolution|resolution]] 1.71&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[3knr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_14579 Atcc 14579]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KNR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KNR FirstGlance]. <br>
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<table><tr><td colspan='2'>[[3knr]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_cereus Bacillus cereus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=3KNR OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=3KNR FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.71&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1bvt|1bvt]], [[1bc2|1bc2]], [[3kns|3kns]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">blm ([https://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1396 ATCC 14579])</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Beta-lactamase Beta-lactamase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.5.2.6 3.5.2.6] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3knr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3knr OCA], [https://pdbe.org/3knr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3knr RCSB], [https://www.ebi.ac.uk/pdbsum/3knr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3knr ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=3knr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3knr OCA], [https://pdbe.org/3knr PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=3knr RCSB], [https://www.ebi.ac.uk/pdbsum/3knr PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=3knr ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/BLA2_BACCE BLA2_BACCE]] Can hydrolyze carbapenem compounds.
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[https://www.uniprot.org/uniprot/BLA2_BACCE BLA2_BACCE] Can hydrolyze carbapenem compounds.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Atcc 14579]]
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[[Category: Bacillus cereus]]
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[[Category: Beta-lactamase]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Gonzalez, J M]]
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[[Category: Gonzalez JM]]
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[[Category: Martin, F J.Medrano]]
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[[Category: Medrano Martin FJ]]
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[[Category: Vila, A J]]
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[[Category: Vila AJ]]
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[[Category: Antibiotic resistance]]
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[[Category: Hydrolase]]
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[[Category: Metal-binding]]
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[[Category: Metallo-beta-lactamase]]
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[[Category: Zn-dependent hydrolase]]
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Revision as of 06:34, 19 July 2023

Bacillus cereus metallo-beta-lactamase Cys221Asp mutant, 1 mM Zn(II)

PDB ID 3knr

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