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5f8u
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5f8u is ON HOLD Authors: Leslie, A.G.W., Warne, A., Tate, C.G. Description: Ligand occupancy in crystal structure of beta1-adrenergic receptor prev...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Ligand occupancy in crystal structure of beta1-adrenergic receptor previously submitted by Huang et al== | |
| + | <StructureSection load='5f8u' size='340' side='right'caption='[[5f8u]], [[Resolution|resolution]] 3.35Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5f8u]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Meleagris_gallopavo Meleagris gallopavo]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5F8U OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5F8U FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.35Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=P32:4-{[(2S)-3-(TERT-BUTYLAMINO)-2-HYDROXYPROPYL]OXY}-3H-INDOLE-2-CARBONITRILE'>P32</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5f8u FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5f8u OCA], [https://pdbe.org/5f8u PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5f8u RCSB], [https://www.ebi.ac.uk/pdbsum/5f8u PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5f8u ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/ADRB1_MELGA ADRB1_MELGA] Beta-adrenergic receptors mediate the catecholamine-induced activation of adenylate cyclase through the action of G proteins. This receptor binds epinephrine and norepinephrine with approximately equal affinity. | ||
| - | + | ==See Also== | |
| - | + | *[[Adrenergic receptor 3D structures|Adrenergic receptor 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Leslie | + | [[Category: Meleagris gallopavo]] |
| - | [[Category: Tate | + | [[Category: Leslie AGW]] |
| + | [[Category: Tate CG]] | ||
| + | [[Category: Warne A]] | ||
Current revision
Ligand occupancy in crystal structure of beta1-adrenergic receptor previously submitted by Huang et al
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