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5fbm

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Current revision (06:45, 19 July 2023) (edit) (undo)
 
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<StructureSection load='5fbm' size='340' side='right'caption='[[5fbm]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='5fbm' size='340' side='right'caption='[[5fbm]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5fbm]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Strmu Strmu]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FBM OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FBM FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5fbm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_mutans_UA159 Streptococcus mutans UA159]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FBM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FBM FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">hup, hlpA, SMU_589 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=210007 STRMU])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fbm OCA], [http://pdbe.org/5fbm PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fbm RCSB], [http://www.ebi.ac.uk/pdbsum/5fbm PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fbm ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fbm OCA], [https://pdbe.org/5fbm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fbm RCSB], [https://www.ebi.ac.uk/pdbsum/5fbm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fbm ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/DBH_STRMU DBH_STRMU]] Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Seems also to act as a fortuitous virulence factor in delayed sequelae by binding to heparan sulfate-proteoglycans in the extracellular matrix of target organs and acting as a nidus for in situ immune complex formation.
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[https://www.uniprot.org/uniprot/DBH_STRMU DBH_STRMU] Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Seems also to act as a fortuitous virulence factor in delayed sequelae by binding to heparan sulfate-proteoglycans in the extracellular matrix of target organs and acting as a nidus for in situ immune complex formation.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Strmu]]
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[[Category: Streptococcus mutans UA159]]
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[[Category: Battaile, K P]]
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[[Category: Battaile KP]]
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[[Category: Biswas, I]]
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[[Category: Biswas I]]
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[[Category: Lovell, S]]
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[[Category: Lovell S]]
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[[Category: Mehzabeen, N]]
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[[Category: Mehzabeen N]]
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[[Category: Neil, P O]]
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[[Category: O'Neil P]]
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[[Category: Dimerization]]
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[[Category: Dna binding]]
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[[Category: Dna binding protein]]
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[[Category: Histone-like protein]]
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Current revision

Crystal Structure of Histone Like Protein (HLP) from Streptococcus mutans Refined to 1.9 A Resolution

PDB ID 5fbm

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