This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5fbm
From Proteopedia
(Difference between revisions)
| Line 3: | Line 3: | ||
<StructureSection load='5fbm' size='340' side='right'caption='[[5fbm]], [[Resolution|resolution]] 1.90Å' scene=''> | <StructureSection load='5fbm' size='340' side='right'caption='[[5fbm]], [[Resolution|resolution]] 1.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5fbm]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5fbm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_mutans_UA159 Streptococcus mutans UA159]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FBM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FBM FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fbm OCA], [https://pdbe.org/5fbm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fbm RCSB], [https://www.ebi.ac.uk/pdbsum/5fbm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fbm ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/DBH_STRMU DBH_STRMU] Histone-like DNA-binding protein which is capable of wrapping DNA to stabilize it, and thus to prevent its denaturation under extreme environmental conditions. Seems also to act as a fortuitous virulence factor in delayed sequelae by binding to heparan sulfate-proteoglycans in the extracellular matrix of target organs and acting as a nidus for in situ immune complex formation. |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 23: | Line 23: | ||
</StructureSection> | </StructureSection> | ||
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: | + | [[Category: Streptococcus mutans UA159]] |
| - | [[Category: Battaile | + | [[Category: Battaile KP]] |
| - | [[Category: Biswas | + | [[Category: Biswas I]] |
| - | [[Category: Lovell | + | [[Category: Lovell S]] |
| - | [[Category: Mehzabeen | + | [[Category: Mehzabeen N]] |
| - | [[Category: Neil | + | [[Category: O'Neil P]] |
| - | + | ||
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
Crystal Structure of Histone Like Protein (HLP) from Streptococcus mutans Refined to 1.9 A Resolution
| |||||||||||
