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8g87

From Proteopedia

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(New page: '''Unreleased structure''' The entry 8g87 is ON HOLD Authors: Description: Category: Unreleased Structures)
Current revision (12:54, 26 July 2023) (edit) (undo)
 
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'''Unreleased structure'''
 
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The entry 8g87 is ON HOLD
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==Human Oct4 bound to nucleosome with human nMatn1 sequence (focused refinement of Oct4 bound region)==
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<StructureSection load='8g87' size='340' side='right'caption='[[8g87]], [[Resolution|resolution]] 5.70&Aring;' scene=''>
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Authors:
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== Structural highlights ==
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<table><tr><td colspan='2'>[[8g87]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8G87 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8G87 FirstGlance]. <br>
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Description:
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 5.7&#8491;</td></tr>
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[[Category: Unreleased Structures]]
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8g87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8g87 OCA], [https://pdbe.org/8g87 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8g87 RCSB], [https://www.ebi.ac.uk/pdbsum/8g87 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8g87 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PO5F1_HUMAN PO5F1_HUMAN] Transcription factor that binds to the octamer motif (5'-ATTTGCAT-3'). Forms a trimeric complex with SOX2 or SOX15 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. Critical for early embryogenesis and for embryonic stem cell pluripotency.<ref>PMID:18035408</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
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[[Category: Homo sapiens]]
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[[Category: Large Structures]]
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[[Category: Bilokapic S]]
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[[Category: Du Y]]
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[[Category: Halic M]]
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[[Category: Malik D]]
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[[Category: Sinha KK]]

Current revision

Human Oct4 bound to nucleosome with human nMatn1 sequence (focused refinement of Oct4 bound region)

PDB ID 8g87

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OCA

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