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5fsj

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==THERMOLYSIN SOAK-AND-FREEZE UNDER 45BAR DIOXYGEN==
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==Structure of thermolysin prepared by the 'soak-and-freeze' method under 45 bar of oxygen pressure==
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<StructureSection load='5fsj' size='340' side='right' caption='[[5fsj]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
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<StructureSection load='5fsj' size='340' side='right'caption='[[5fsj]], [[Resolution|resolution]] 1.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5fsj]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FSJ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FSJ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5fsj]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_thermoproteolyticus Bacillus thermoproteolyticus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FSJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FSJ FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=VAL:VALINE'>VAL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.201&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5fsp|5fsp]], [[5fss|5fss]], [[5fst|5fst]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=LYS:LYSINE'>LYS</scene>, <scene name='pdbligand=OXY:OXYGEN+MOLECULE'>OXY</scene>, <scene name='pdbligand=VAL:VALINE'>VAL</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thermolysin Thermolysin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.27 3.4.24.27] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fsj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fsj OCA], [https://pdbe.org/5fsj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fsj RCSB], [https://www.ebi.ac.uk/pdbsum/5fsj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fsj ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5fsj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fsj OCA], [http://pdbe.org/5fsj PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5fsj RCSB], [http://www.ebi.ac.uk/pdbsum/5fsj PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5fsj ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/THER_BACTH THER_BACTH]] Extracellular zinc metalloprotease.
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[https://www.uniprot.org/uniprot/THER_BACTH THER_BACTH] Extracellular zinc metalloprotease.
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==See Also==
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*[[Thermolysin 3D structures|Thermolysin 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Thermolysin]]
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[[Category: Bacillus thermoproteolyticus]]
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[[Category: Carpentier, P]]
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[[Category: Large Structures]]
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[[Category: Colloch, N]]
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[[Category: Carpentier P]]
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[[Category: Lafumat, B]]
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[[Category: Colloc'h N]]
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[[Category: Linden, P Van Der]]
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[[Category: Lafumat B]]
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[[Category: Mueller-Dieckmann, C]]
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[[Category: Mueller-Dieckmann C]]
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[[Category: Prange, T]]
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[[Category: Prange T]]
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[[Category: Royant, A]]
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[[Category: Royant A]]
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[[Category: Dioxygen]]
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[[Category: Van der Linden P]]
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[[Category: Flash freezing]]
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[[Category: Hydrolase]]
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[[Category: Metalloproteinase]]
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[[Category: Pressure]]
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[[Category: Thermolysine]]
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Current revision

Structure of thermolysin prepared by the 'soak-and-freeze' method under 45 bar of oxygen pressure

PDB ID 5fsj

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