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5ftp

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==sulfur SAD phasing of Cdc23Nterm: data collection with a tailored X- ray beam size at 2.69 A wavelength (4.6 keV)==
==sulfur SAD phasing of Cdc23Nterm: data collection with a tailored X- ray beam size at 2.69 A wavelength (4.6 keV)==
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<StructureSection load='5ftp' size='340' side='right' caption='[[5ftp]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
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<StructureSection load='5ftp' size='340' side='right'caption='[[5ftp]], [[Resolution|resolution]] 3.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ftp]] is a 2 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FTP OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5FTP FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ftp]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FTP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FTP FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ftp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ftp OCA], [http://pdbe.org/5ftp PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ftp RCSB], [http://www.ebi.ac.uk/pdbsum/5ftp PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ftp ProSAT]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.1&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ftp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ftp OCA], [https://pdbe.org/5ftp PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ftp RCSB], [https://www.ebi.ac.uk/pdbsum/5ftp PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ftp ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/APC8_SCHPO APC8_SCHPO]] Component of the anaphase-promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome. Has a role in promoting metaphase to anaphase transition via the ubiquitination of specific mitotic substrates.<ref>PMID:10526233</ref>
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[https://www.uniprot.org/uniprot/APC8_SCHPO APC8_SCHPO] Component of the anaphase-promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin-protein ligase complex that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C is thought to confer substrate specificity and, in the presence of ubiquitin-conjugating E2 enzymes, it catalyzes the formation of protein-ubiquitin conjugates that are subsequently degraded by the 26S proteasome. Has a role in promoting metaphase to anaphase transition via the ubiquitination of specific mitotic substrates.<ref>PMID:10526233</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Barford, D]]
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[[Category: Large Structures]]
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[[Category: Cianci, M]]
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[[Category: Schizosaccharomyces pombe]]
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[[Category: Groves, M R]]
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[[Category: Barford D]]
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[[Category: Schneider, T R]]
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[[Category: Cianci M]]
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[[Category: Cell cycle]]
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[[Category: Groves MR]]
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[[Category: Long wavelength]]
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[[Category: Schneider TR]]
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[[Category: Low resolution]]
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[[Category: Sad phasing]]
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[[Category: Soft x-ray]]
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[[Category: Sulfur]]
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Current revision

sulfur SAD phasing of Cdc23Nterm: data collection with a tailored X- ray beam size at 2.69 A wavelength (4.6 keV)

PDB ID 5ftp

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