5fv8
From Proteopedia
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- | '''Unreleased structure''' | ||
- | + | ==Structure of cJun-FosW coiled coil complex.== | |
+ | <StructureSection load='5fv8' size='340' side='right'caption='[[5fv8]], [[Resolution|resolution]] 1.99Å' scene=''> | ||
+ | == Structural highlights == | ||
+ | <table><tr><td colspan='2'>[[5fv8]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FV8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FV8 FirstGlance]. <br> | ||
+ | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.99Å</td></tr> | ||
+ | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=JEF:O-(O-(2-AMINOPROPYL)-O-(2-METHOXYETHYL)POLYPROPYLENE+GLYCOL+500)'>JEF</scene></td></tr> | ||
+ | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fv8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fv8 OCA], [https://pdbe.org/5fv8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fv8 RCSB], [https://www.ebi.ac.uk/pdbsum/5fv8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fv8 ProSAT]</span></td></tr> | ||
+ | </table> | ||
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/JUN_HUMAN JUN_HUMAN] Transcription factor that recognizes and binds to the enhancer heptamer motif 5'-TGA[CG]TCA-3'. Promotes activity of NR5A1 when phosphorylated by HIPK3 leading to increased steroidogenic gene expression upon cAMP signaling pathway stimulation.<ref>PMID:10995748</ref> <ref>PMID:17210646</ref> | ||
- | + | ==See Also== | |
- | + | *[[C-JUN|C-JUN]] | |
- | + | == References == | |
- | [[Category: | + | <references/> |
- | [[Category: | + | __TOC__ |
- | [[Category: | + | </StructureSection> |
- | [[Category: Zaccai | + | [[Category: Homo sapiens]] |
+ | [[Category: Large Structures]] | ||
+ | [[Category: Brady RL]] | ||
+ | [[Category: Mason JM]] | ||
+ | [[Category: Zaccai NR]] |
Current revision
Structure of cJun-FosW coiled coil complex.
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