This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
5fwb
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 5fwb is ON HOLD until sometime in the future Authors: Gallego, P., Navarro, S., Ventura, S., Reverter, D. Description: Human Spectrin SH3 domain D4...) |
|||
| (5 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
| - | '''Unreleased structure''' | ||
| - | + | ==Human Spectrin SH3 domain D48G, E7F, K60F== | |
| + | <StructureSection load='5fwb' size='340' side='right'caption='[[5fwb]], [[Resolution|resolution]] 1.50Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[5fwb]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5FWB OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5FWB FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5fwb FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5fwb OCA], [https://pdbe.org/5fwb PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5fwb RCSB], [https://www.ebi.ac.uk/pdbsum/5fwb PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5fwb ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/SPTN1_HUMAN SPTN1_HUMAN] West syndrome. The disease is caused by mutations affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/SPTN1_HUMAN SPTN1_HUMAN] Fodrin, which seems to be involved in secretion, interacts with calmodulin in a calcium-dependent manner and is thus candidate for the calcium-dependent movement of the cytoskeleton at the membrane. | ||
| - | + | ==See Also== | |
| - | + | *[[Spectrin 3D structures|Spectrin 3D structures]] | |
| - | + | __TOC__ | |
| - | [[Category: | + | </StructureSection> |
| - | [[Category: Gallego | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Gallego P]] |
| - | [[Category: Ventura | + | [[Category: Navarro S]] |
| + | [[Category: Reverter D]] | ||
| + | [[Category: Ventura S]] | ||
Current revision
Human Spectrin SH3 domain D48G, E7F, K60F
| |||||||||||
