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7xuh
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 7xuh is ON HOLD Authors: Description: Category: Unreleased Structures) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Down-regulated in adenoma in complex with TQR1122== | |
| - | + | <StructureSection load='7xuh' size='340' side='right'caption='[[7xuh]], [[Resolution|resolution]] 2.76Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[7xuh]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=7XUH OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=7XUH FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.76Å</td></tr> | |
| - | [[Category: | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=I2L:2-[4,8-dimethyl-2-oxidanylidene-7-[[3-(trifluoromethyl)phenyl]methoxy]chromen-3-yl]ethanoic+acid'>I2L</scene>, <scene name='pdbligand=Y01:CHOLESTEROL+HEMISUCCINATE'>Y01</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=7xuh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=7xuh OCA], [https://pdbe.org/7xuh PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=7xuh RCSB], [https://www.ebi.ac.uk/pdbsum/7xuh PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=7xuh ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Disease == | ||
| + | [https://www.uniprot.org/uniprot/S26A3_HUMAN S26A3_HUMAN] Congenital chloride diarrhea. The disease is caused by variants affecting the gene represented in this entry. | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/S26A3_HUMAN S26A3_HUMAN] Mediates chloride-bicarbonate exchange with a chloride bicarbonate stoichiometry of 2:1 in the intestinal epithelia (PubMed:16606687, PubMed:19321737, PubMed:22159084, PubMed:22627094). Plays a role in the chloride and bicarbonate homeostasis during sperm epididymal maturation and capacitation (By similarity).[UniProtKB:Q9WVC8]<ref>PMID:16606687</ref> <ref>PMID:19321737</ref> <ref>PMID:22159084</ref> <ref>PMID:22627094</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Chi XM]] | ||
| + | [[Category: Li XR]] | ||
| + | [[Category: Zhang YY]] | ||
| + | [[Category: Zhou Q]] | ||
Current revision
Down-regulated in adenoma in complex with TQR1122
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Categories: Homo sapiens | Large Structures | Chi XM | Li XR | Zhang YY | Zhou Q
