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1bkl

From Proteopedia

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[[Image:1bkl.png|left|200px]]
 
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{{STRUCTURE_1bkl| PDB=1bkl | SCENE= }}
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==SELF-ASSOCIATED APO SRC SH2 DOMAIN==
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<StructureSection load='1bkl' size='340' side='right'caption='[[1bkl]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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===SELF-ASSOCIATED APO SRC SH2 DOMAIN===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1bkl]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BKL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BKL FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bkl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bkl OCA], [https://pdbe.org/1bkl PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bkl RCSB], [https://www.ebi.ac.uk/pdbsum/1bkl PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bkl ProSAT]</span></td></tr>
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[[1bkl]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BKL OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SRC_RSVSA SRC_RSVSA] This phosphoprotein, required for both the initiation and the maintenance of neoplastic transformation, is a protein kinase that catalyzes the phosphorylation of tyrosine residues in vitro.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bk/1bkl_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bkl ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Rous sarcoma virus]]
[[Category: Rous sarcoma virus]]
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[[Category: Transferase]]
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[[Category: Holland DR]]
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[[Category: Holland, D R.]]
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[[Category: Rubin JR]]
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[[Category: Rubin, J R.]]
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[[Category: Phosphotyrosine recognition domain]]
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[[Category: Pp60 src sh2 domain]]
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[[Category: V-src sh2 domain]]
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Current revision

SELF-ASSOCIATED APO SRC SH2 DOMAIN

PDB ID 1bkl

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