This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5gk8

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:34, 2 August 2023) (edit) (undo)
 
Line 1: Line 1:
==Structure of E.Coli fructose 1,6-bisphosphate aldolase, Acetate bound form==
==Structure of E.Coli fructose 1,6-bisphosphate aldolase, Acetate bound form==
-
<StructureSection load='5gk8' size='340' side='right' caption='[[5gk8]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
+
<StructureSection load='5gk8' size='340' side='right'caption='[[5gk8]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5gk8]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GK8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GK8 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5gk8]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GK8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5GK8 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.002&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">fbaA, fba, fda, b2925, JW2892 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=83333 ECOLI])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ACT:ACETATE+ION'>ACT</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Fructose-bisphosphate_aldolase Fructose-bisphosphate aldolase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.2.13 4.1.2.13] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5gk8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gk8 OCA], [https://pdbe.org/5gk8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5gk8 RCSB], [https://www.ebi.ac.uk/pdbsum/5gk8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5gk8 ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gk8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gk8 OCA], [http://pdbe.org/5gk8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gk8 RCSB], [http://www.ebi.ac.uk/pdbsum/5gk8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gk8 ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/ALF_ECOLI ALF_ECOLI]] Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.<ref>PMID:10712619</ref>
+
[https://www.uniprot.org/uniprot/ALF_ECOLI ALF_ECOLI] Catalyzes the aldol condensation of dihydroxyacetone phosphate (DHAP or glycerone-phosphate) with glyceraldehyde 3-phosphate (G3P) to form fructose 1,6-bisphosphate (FBP) in gluconeogenesis and the reverse reaction in glycolysis.<ref>PMID:10712619</ref>
 +
 
 +
==See Also==
 +
*[[Aldolase 3D structures|Aldolase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Ecoli]]
+
[[Category: Escherichia coli K-12]]
-
[[Category: Fructose-bisphosphate aldolase]]
+
[[Category: Large Structures]]
-
[[Category: Ho, T H]]
+
[[Category: Ho TH]]
-
[[Category: Huynh, K H]]
+
[[Category: Huynh KH]]
-
[[Category: Kang, L W]]
+
[[Category: Kang LW]]
-
[[Category: Tran, T H]]
+
[[Category: Tran TH]]
-
[[Category: Fba acetate bound]]
+
-
[[Category: Lyase]]
+

Current revision

Structure of E.Coli fructose 1,6-bisphosphate aldolase, Acetate bound form

PDB ID 5gk8

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools