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5gmi

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Current revision (11:36, 2 August 2023) (edit) (undo)
 
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==Crystal Structure of GRASP55 GRASP domain in complex with JAM-C C-terminus==
==Crystal Structure of GRASP55 GRASP domain in complex with JAM-C C-terminus==
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<StructureSection load='5gmi' size='340' side='right' caption='[[5gmi]], [[Resolution|resolution]] 2.71&Aring;' scene=''>
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<StructureSection load='5gmi' size='340' side='right'caption='[[5gmi]], [[Resolution|resolution]] 2.71&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5gmi]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GMI OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5GMI FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5gmi]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5GMI OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5GMI FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5gmj|5gmj]], [[5gml|5gml]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.71&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Gorasp2,GOLPH6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=10090 LK3 transgenic mice])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5gmi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gmi OCA], [https://pdbe.org/5gmi PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5gmi RCSB], [https://www.ebi.ac.uk/pdbsum/5gmi PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5gmi ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5gmi FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5gmi OCA], [http://pdbe.org/5gmi PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5gmi RCSB], [http://www.ebi.ac.uk/pdbsum/5gmi PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5gmi ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GORS2_MOUSE GORS2_MOUSE]] Plays a role in assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after mitotic breakdown. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA.<ref>PMID:10487747</ref> [[http://www.uniprot.org/uniprot/JAM3_MOUSE JAM3_MOUSE]] Participates in cell-cell adhesion. It is a counter-receptor for ITGAM mediating leukocyte-platelet interactions and is involved in the regulation of transepithelial migration of polymorphonuclear neutrophils (PMN) (By similarity). The soluble form is a mediator of angiogenesis.<ref>PMID:11739175</ref> <ref>PMID:15994945</ref> <ref>PMID:20592283</ref>
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[https://www.uniprot.org/uniprot/GORS2_MOUSE GORS2_MOUSE] Plays a role in assembly and membrane stacking of the Golgi cisternae, and in the process by which Golgi stacks reform after mitotic breakdown. May regulate the intracellular transport and presentation of a defined set of transmembrane proteins, such as transmembrane TGFA.<ref>PMID:10487747</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5gmi" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5gmi" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Glycosyltransferase 3D structures|Glycosyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Lk3 transgenic mice]]
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[[Category: Large Structures]]
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[[Category: Betzi, S]]
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[[Category: Mus musculus]]
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[[Category: Huang, X]]
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[[Category: Betzi S]]
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[[Category: Morelli, X]]
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[[Category: Huang X]]
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[[Category: Shi, N]]
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[[Category: Morelli X]]
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[[Category: Shi, X]]
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[[Category: Shi N]]
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[[Category: Beta strand sandswish]]
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[[Category: Shi X]]
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[[Category: Classic pdz peptide binding groove]]
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[[Category: Conserved carboxylate-binding loop]]
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[[Category: Structural protein-peptide complex]]
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Current revision

Crystal Structure of GRASP55 GRASP domain in complex with JAM-C C-terminus

PDB ID 5gmi

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