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1bqy

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==Plasminogen activator (TSV-PA) from snake venom==
==Plasminogen activator (TSV-PA) from snake venom==
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<StructureSection load='1bqy' size='340' side='right' caption='[[1bqy]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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<StructureSection load='1bqy' size='340' side='right'caption='[[1bqy]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1bqy]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Viridovipera_stejnegeri Viridovipera stejnegeri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BQY OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1BQY FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1bqy]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Trimeresurus_stejnegeri Trimeresurus stejnegeri]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1BQY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1BQY FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=0GJ:L-ALPHA-GLUTAMYL-N-{(1S)-4-{[AMINO(IMINIO)METHYL]AMINO}-1-[(1S)-2-CHLORO-1-HYDROXYETHYL]BUTYL}GLYCINAMIDE'>0GJ</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1bqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bqy OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1bqy RCSB], [http://www.ebi.ac.uk/pdbsum/1bqy PDBsum]</span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=0GJ:L-ALPHA-GLUTAMYL-N-{(1S)-4-{[AMINO(IMINIO)METHYL]AMINO}-1-[(1S)-2-CHLORO-1-HYDROXYETHYL]BUTYL}GLYCINAMIDE'>0GJ</scene></td></tr>
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<table>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1bqy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1bqy OCA], [https://pdbe.org/1bqy PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1bqy RCSB], [https://www.ebi.ac.uk/pdbsum/1bqy PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1bqy ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/VSPPA_TRIST VSPPA_TRIST] Snake venom serine protease that activates plasminogen.<ref>PMID:7730329</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bq/1bqy_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/bq/1bqy_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1bqy ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1bqy" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Viridovipera stejnegeri]]
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[[Category: Large Structures]]
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[[Category: Bode, W.]]
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[[Category: Trimeresurus stejnegeri]]
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[[Category: Parry, M A.A.]]
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[[Category: Bode W]]
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[[Category: Blood clotting]]
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[[Category: Parry MAA]]
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[[Category: Fibrinolysis]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Plasminogen activator]]
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[[Category: Serine proteinase]]
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[[Category: Snake venom]]
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Current revision

Plasminogen activator (TSV-PA) from snake venom

PDB ID 1bqy

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