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1i6n

From Proteopedia

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[[Image:1i6n.gif|left|200px]]
 
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{{Structure
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==1.8 A Crystal structure of IOLI protein with a binding zinc atom==
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|PDB= 1i6n |SIZE=350|CAPTION= <scene name='initialview01'>1i6n</scene>, resolution 1.80&Aring;
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<StructureSection load='1i6n' size='340' side='right'caption='[[1i6n]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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<table><tr><td colspan='2'>[[1i6n]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I6N OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1I6N FirstGlance]. <br>
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|ACTIVITY=
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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|GENE= IOLI OR B65B ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1423 Bacillus subtilis])
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr>
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|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00019 AP2Ec], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=COG1082 IolE]</span>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1i6n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i6n OCA], [https://pdbe.org/1i6n PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1i6n RCSB], [https://www.ebi.ac.uk/pdbsum/1i6n PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1i6n ProSAT], [https://www.topsan.org/Proteins/MCSG/1i6n TOPSAN]</span></td></tr>
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|RELATEDENTRY=[[1i60|1I60]]
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</table>
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1i6n FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1i6n OCA], [http://www.ebi.ac.uk/pdbsum/1i6n PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1i6n RCSB]</span>
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== Function ==
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}}
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[https://www.uniprot.org/uniprot/IOLI_BACSU IOLI_BACSU] Involved in the reversible interconverion of 2-keto-myo-inositol (2KMI, inosose or 2,4,6/3,5-pentahydroxycyclohexanone) to 1-keto-D-chiro-inositol (1KDCI or 2,3,5/4,6-pentahydroxycyclohexanone).
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== Evolutionary Conservation ==
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'''1.8 A Crystal structure of IOLI protein with a binding zinc atom'''
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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==About this Structure==
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/i6/1i6n_consurf.spt"</scriptWhenChecked>
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1I6N is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Bacillus_subtilis Bacillus subtilis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1I6N OCA].
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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==Reference==
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</jmolCheckbox>
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Crystal structure of Bacillus subtilis ioli shows endonuclase IV fold with altered Zn binding., Zhang RG, Dementieva I, Duke N, Collart F, Quaite-Randall E, Alkire R, Dieckman L, Maltsev N, Korolev O, Joachimiak A, Proteins. 2002 Aug 1;48(2):423-6. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/12112707 12112707]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1i6n ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
[[Category: Bacillus subtilis]]
[[Category: Bacillus subtilis]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Alkire, R.]]
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[[Category: Alkire R]]
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[[Category: Collart, F.]]
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[[Category: Collart F]]
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[[Category: Dementiva, I.]]
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[[Category: Dementiva I]]
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[[Category: Dieckman, L.]]
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[[Category: Dieckman L]]
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[[Category: Joachimiak, A.]]
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[[Category: Joachimiak A]]
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[[Category: Korolev, O.]]
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[[Category: Korolev O]]
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[[Category: MCSG, Midwest Center for Structural Genomics.]]
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[[Category: Maltsev N]]
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[[Category: Maltsev, N.]]
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[[Category: Quaite-Randall E]]
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[[Category: Quaite-Randall, E.]]
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[[Category: Zhang RG]]
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[[Category: Zhang, R G.]]
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[[Category: beta barrel]]
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[[Category: mcsg]]
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[[Category: midwest center for structural genomic]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun Mar 30 21:15:21 2008''
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Current revision

1.8 A Crystal structure of IOLI protein with a binding zinc atom

PDB ID 1i6n

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