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1vip
From Proteopedia
(Difference between revisions)
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<StructureSection load='1vip' size='340' side='right'caption='[[1vip]], [[Resolution|resolution]] 2.20Å' scene=''> | <StructureSection load='1vip' size='340' side='right'caption='[[1vip]], [[Resolution|resolution]] 2.20Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1vip]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/ | + | <table><tr><td colspan='2'>[[1vip]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Daboia_russelii_russelii Daboia russelii russelii]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1VIP OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1VIP FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vip FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vip OCA], [https://pdbe.org/1vip PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vip RCSB], [https://www.ebi.ac.uk/pdbsum/1vip PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vip ProSAT]</span></td></tr> | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1vip FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1vip OCA], [https://pdbe.org/1vip PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1vip RCSB], [https://www.ebi.ac.uk/pdbsum/1vip PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1vip ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | + | [https://www.uniprot.org/uniprot/PA2B_DABRR PA2B_DABRR] Snake venom phospholipase A2 (PLA2) that has low enzymatic activity, is devoid of lethal activity but has strong anticoagulant activity. PLA2 catalyzes the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides.<ref>PMID:8835338</ref> | |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Daboia | + | [[Category: Daboia russelii russelii]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Carredano | + | [[Category: Carredano E]] |
| - | [[Category: Eaker | + | [[Category: Eaker D]] |
| - | [[Category: Eklund | + | [[Category: Eklund H]] |
| - | [[Category: Persson | + | [[Category: Persson B]] |
| - | [[Category: Ramaswamy | + | [[Category: Ramaswamy S]] |
| - | [[Category: Saarinen | + | [[Category: Saarinen M]] |
| - | [[Category: Westerlund | + | [[Category: Westerlund B]] |
| - | + | ||
| - | + | ||
| - | + | ||
Current revision
ANTICOAGULANT CLASS II PHOSPHOLIPASE A2 FROM THE VENOM OF VIPERA RUSSELLI RUSSELLI
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