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2x12
From Proteopedia
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| - | <StructureSection load='2x12' size='340' side='right' caption='[[2x12]], [[Resolution|resolution]] 2.90Å' scene=''> | + | ==pH-induced modulation of Streptococcus parasanguinis adhesion by Fap1 fimbriae== |
| + | <StructureSection load='2x12' size='340' side='right'caption='[[2x12]], [[Resolution|resolution]] 2.90Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2x12]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2x12]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_parasanguinis Streptococcus parasanguinis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X12 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X12 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x12 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x12 OCA], [https://pdbe.org/2x12 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x12 RCSB], [https://www.ebi.ac.uk/pdbsum/2x12 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x12 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/FAP1_STRPA FAP1_STRPA] The major structural element of fimbriae. Required for adherence to saliva-coated hydroxyapatite beads (SHA), an in vitro tooth model. A Fap1-dependent increase in adherence is seen as the pH is reduced from pH 8 to pH 5.<ref>PMID:10594831</ref> <ref>PMID:9632253</ref> | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2x12" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| + | [[Category: Large Structures]] | ||
[[Category: Streptococcus parasanguinis]] | [[Category: Streptococcus parasanguinis]] | ||
| - | [[Category: Garnett | + | [[Category: Garnett J]] |
| - | [[Category: Matthews | + | [[Category: Matthews S]] |
| - | [[Category: Murray | + | [[Category: Murray JW]] |
| - | [[Category: Ramboarina | + | [[Category: Ramboarina S]] |
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Current revision
pH-induced modulation of Streptococcus parasanguinis adhesion by Fap1 fimbriae
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