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5hel
From Proteopedia
(Difference between revisions)
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<StructureSection load='5hel' size='340' side='right'caption='[[5hel]], [[Resolution|resolution]] 1.45Å' scene=''> | <StructureSection load='5hel' size='340' side='right'caption='[[5hel]], [[Resolution|resolution]] 1.45Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[5hel]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[5hel]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HEL OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HEL FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.45Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hel FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hel OCA], [https://pdbe.org/5hel PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hel RCSB], [https://www.ebi.ac.uk/pdbsum/5hel PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hel ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/BRD2_HUMAN BRD2_HUMAN] May play a role in spermatogenesis or folliculogenesis (By similarity). Binds hyperacetylated chromatin and plays a role in the regulation of transcription, probably by chromatin remodeling. Regulates transcription of the CCND1 gene. Plays a role in nucleosome assembly.<ref>PMID:18406326</ref> |
==See Also== | ==See Also== | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
[[Category: Large Structures]] | [[Category: Large Structures]] | ||
| - | [[Category: Arrowsmith | + | [[Category: Arrowsmith CH]] |
| - | [[Category: Bountra | + | [[Category: Bountra C]] |
| - | [[Category: Chiaraluce | + | [[Category: Chiaraluce R]] |
| - | [[Category: Consalvi | + | [[Category: Consalvi V]] |
| - | + | [[Category: Edwards AM]] | |
| - | [[Category: Edwards | + | [[Category: Knapp S]] |
| - | [[Category: Knapp | + | [[Category: Lori C]] |
| - | [[Category: Lori | + | [[Category: Newman JA]] |
| - | [[Category: Newman | + | [[Category: Pasquo A]] |
| - | [[Category: Pasquo | + | [[Category: Tallant C]] |
| - | [[Category: Tallant | + | [[Category: Von Delft F]] |
| - | [[Category: | + | |
| - | + | ||
| - | + | ||
Current revision
Crystal structure of the N-terminus Y153H bromodomain mutant of human BRD2
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Categories: Homo sapiens | Large Structures | Arrowsmith CH | Bountra C | Chiaraluce R | Consalvi V | Edwards AM | Knapp S | Lori C | Newman JA | Pasquo A | Tallant C | Von Delft F
