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1k7y

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==E. coli MetH C-terminal fragment (649-1227)==
==E. coli MetH C-terminal fragment (649-1227)==
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<StructureSection load='1k7y' size='340' side='right' caption='[[1k7y]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
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<StructureSection load='1k7y' size='340' side='right'caption='[[1k7y]], [[Resolution|resolution]] 3.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1k7y]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K7Y OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1K7Y FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1k7y]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1K7Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1K7Y FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1msk|1msk]], [[1bmt|1bmt]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=B12:COBALAMIN'>B12</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Escherichia coli ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 "Bacillus coli" Migula 1895])</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1k7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k7y OCA], [https://pdbe.org/1k7y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1k7y RCSB], [https://www.ebi.ac.uk/pdbsum/1k7y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1k7y ProSAT]</span></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Methionine_synthase Methionine synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.13 2.1.1.13] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1k7y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1k7y OCA], [http://pdbe.org/1k7y PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1k7y RCSB], [http://www.ebi.ac.uk/pdbsum/1k7y PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1k7y ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/METH_ECOLI METH_ECOLI]] Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
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[https://www.uniprot.org/uniprot/METH_ECOLI METH_ECOLI] Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</div>
</div>
<div class="pdbe-citations 1k7y" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1k7y" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Methionine synthase 3D structures|Methionine synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
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[[Category: Methionine synthase]]
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[[Category: Large Structures]]
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[[Category: Bandarian, V]]
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[[Category: Bandarian V]]
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[[Category: Huddler, D P]]
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[[Category: Huddler DP]]
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[[Category: Lennon, B W]]
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[[Category: Lennon BW]]
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[[Category: Ludwig, M L]]
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[[Category: Ludwig ML]]
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[[Category: Matthews, R G]]
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[[Category: Matthews RG]]
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[[Category: Pattridge, K A]]
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[[Category: Pattridge KA]]
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[[Category: Domain interaction]]
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[[Category: Motion of 4-helix bundle]]
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[[Category: Transferase]]
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Current revision

E. coli MetH C-terminal fragment (649-1227)

PDB ID 1k7y

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