1opo

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{{Seed}}
 
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[[Image:1opo.png|left|200px]]
 
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==THE STRUCTURE OF CARNATION MOTTLE VIRUS==
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The line below this paragraph, containing "STRUCTURE_1opo", creates the "Structure Box" on the page.
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<StructureSection load='1opo' size='340' side='right'caption='[[1opo]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[1opo]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Carnation_mottle_virus Carnation mottle virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OPO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1OPO FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_1opo| PDB=1opo | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1opo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1opo OCA], [https://pdbe.org/1opo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1opo RCSB], [https://www.ebi.ac.uk/pdbsum/1opo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1opo ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CAPSD_CARMV CAPSD_CARMV] Capsid protein self-assembles to form an icosahedral capsid with a T=3 symmetry, about 32-35 nm in diameter, and consisting of 180 capsid proteins. Also acts as a suppressor of RNA-mediated gene silencing, also known as post-transcriptional gene silencing (PTGS), a mechanism of plant viral defense that limits the accumulation of viral RNAs (By similarity).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/op/1opo_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1opo ConSurf].
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<div style="clear:both"></div>
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<div style="background-color:#fffaf0;">
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== Publication Abstract from PubMed ==
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The structure of the Carnation Mottle Virus (CMtV) capsid protein has been determined at 3.2 A resolution by the method of molecular replacement. Three-dimensional data were collected from a small number of crystals (sp.g. I23, a = 382.6 A) using the synchrotron radiation with an image plate as detector. The coordinates of Tomato Bushy Stunt Virus (TBSV) were used as a searching model. Refinement of the coordinates of 7,479 non-hydrogen atoms performed by the program XPLOR, has led to an R-factor of 18.3%. It was found that the amino acid chain fold of capsid protein is very similar to that in other icosahedral viruses. However, there are some differences in the contact regions between protein subunits and also the lack of the beta-annulus around the 3-fold icosahedral axes. The structural and biochemical results lead us to consider an alternative assembly pathway.
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===THE STRUCTURE OF CARNATION MOTTLE VIRUS===
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The atomic structure of Carnation Mottle Virus capsid protein.,Morgunova EYu, Dauter Z, Fry E, Stuart DI, Stel'mashchuk VYa, Mikhailov AM, Wilson KS, Vainshtein BK FEBS Lett. 1994 Feb 7;338(3):267-71. PMID:8307192<ref>PMID:8307192</ref>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
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</div>
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<div class="pdbe-citations 1opo" style="background-color:#fffaf0;"></div>
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==See Also==
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The line below this paragraph, {{ABSTRACT_PUBMED_8307192}}, adds the Publication Abstract to the page
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*[[Virus coat proteins 3D structures|Virus coat proteins 3D structures]]
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(as it appears on PubMed at http://www.pubmed.gov), where 8307192 is the PubMed ID number.
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== References ==
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<references/>
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{{ABSTRACT_PUBMED_8307192}}
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__TOC__
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</StructureSection>
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==About this Structure==
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1OPO is a 3 chains structure of sequences from [http://en.wikipedia.org/wiki/Carnation_mottle_virus Carnation mottle virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1OPO OCA].
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==Reference==
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<ref group="xtra">PMID:8307192</ref><references group="xtra"/>
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[[Category: Carnation mottle virus]]
[[Category: Carnation mottle virus]]
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[[Category: Dauter, Z.]]
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[[Category: Large Structures]]
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[[Category: Fry, E.]]
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[[Category: Dauter Z]]
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[[Category: Mikhailov, A M.]]
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[[Category: Fry E]]
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[[Category: Morgunova, E.]]
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[[Category: Mikhailov AM]]
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[[Category: Stuart, D.]]
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[[Category: Morgunova E]]
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[[Category: Vainshtein, B K.]]
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[[Category: Stel'mashchuk V]]
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[[Category: Wilson, K S.]]
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[[Category: Stuart D]]
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[[Category: Mashchuk, V Stel.]]
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[[Category: Vainshtein BK]]
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[[Category: Carmovirus]]
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[[Category: Wilson KS]]
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[[Category: Icosahedral virus]]
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[[Category: Plant virus]]
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[[Category: Tomato bushy stunt virus]]
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[[Category: Virus/viral protein]]
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[[Category: X-ray diffraction]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Feb 16 20:03:38 2009''
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Current revision

THE STRUCTURE OF CARNATION MOTTLE VIRUS

PDB ID 1opo

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