1pd5

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[[Image:1pd5.gif|left|200px]]
 
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{{Structure
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==Crystal structure of E.coli chloramphenicol acetyltransferase type I at 2.5 Angstrom resolution==
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|PDB= 1pd5 |SIZE=350|CAPTION= <scene name='initialview01'>1pd5</scene>, resolution 2.50&Aring;
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<StructureSection load='1pd5' size='340' side='right'caption='[[1pd5]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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|SITE=
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== Structural highlights ==
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|LIGAND=
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<table><tr><td colspan='2'>[[1pd5]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PD5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1PD5 FirstGlance]. <br>
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|ACTIVITY= [http://en.wikipedia.org/wiki/Chloramphenicol_O-acetyltransferase Chloramphenicol O-acetyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.28 2.3.1.28]
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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|GENE= CAT OR HCM1.206 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1pd5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1pd5 OCA], [https://pdbe.org/1pd5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1pd5 RCSB], [https://www.ebi.ac.uk/pdbsum/1pd5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1pd5 ProSAT]</span></td></tr>
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}}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CAT_ECOLX CAT_ECOLX] This enzyme is an effector of chloramphenicol resistance in bacteria.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/pd/1pd5_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1pd5 ConSurf].
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<div style="clear:both"></div>
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'''Crystal structure of E.coli chloramphenicol acetyltransferase type I at 2.5 Angstrom resolution'''
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==See Also==
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*[[Chloramphenicol acetyltransferase 3D structures|Chloramphenicol acetyltransferase 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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1PD5 is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1PD5 OCA].
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[[Category: Chloramphenicol O-acetyltransferase]]
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[[Category: Escherichia coli]]
[[Category: Escherichia coli]]
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[[Category: Single protein]]
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[[Category: Large Structures]]
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[[Category: Kokkinidis, M.]]
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[[Category: Kokkinidis M]]
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[[Category: Roidis, A.]]
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[[Category: Roidis A]]
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[[Category: acetyltransferase]]
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[[Category: chloramphenicol]]
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[[Category: trimer]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Mar 20 13:22:50 2008''
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Current revision

Crystal structure of E.coli chloramphenicol acetyltransferase type I at 2.5 Angstrom resolution

PDB ID 1pd5

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