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2kx3
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==The solution structure of the mutant of UBL domain of UBLCP1, I5M== | ==The solution structure of the mutant of UBL domain of UBLCP1, I5M== | ||
| - | <StructureSection load='2kx3' size='340' side='right' caption='[[2kx3 | + | <StructureSection load='2kx3' size='340' side='right'caption='[[2kx3]]' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2kx3]] is a 1 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2kx3]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2KX3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2KX3 FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr> |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2kx3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2kx3 OCA], [https://pdbe.org/2kx3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2kx3 RCSB], [https://www.ebi.ac.uk/pdbsum/2kx3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2kx3 ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/UBCP1_HUMAN UBCP1_HUMAN] Dephosphorylates 26S nuclear proteasomes, thereby decreasing their proteolytic activity. The dephosphorylation may prevent assembly of the core and regulatory particles (CP and RP) into mature 26S proteasome.<ref>PMID:15883030</ref> <ref>PMID:21949367</ref> |
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Ko | + | [[Category: Ko S]] |
| - | [[Category: Lee | + | [[Category: Lee N]] |
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Current revision
The solution structure of the mutant of UBL domain of UBLCP1, I5M
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