This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


5hsa

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (10:52, 16 August 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
-
{{Large structure}}
+
 
==Alcohol Oxidase AOX1 from Pichia Pastoris==
==Alcohol Oxidase AOX1 from Pichia Pastoris==
-
<StructureSection load='5hsa' size='340' side='right' caption='[[5hsa]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
+
<StructureSection load='5hsa' size='340' side='right'caption='[[5hsa]], [[Resolution|resolution]] 2.35&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[5hsa]] is a 8 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HSA OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5HSA FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[5hsa]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Komagataella_phaffii_CBS_7435 Komagataella phaffii CBS 7435]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5HSA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5HSA FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FAS:ARABINO-FLAVIN-ADENINE+DINUCLEOTIDE'>FAS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.35&#8491;</td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Alcohol_oxidase Alcohol oxidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.3.13 1.1.3.13] </span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=FAS:ARABINO-FLAVIN-ADENINE+DINUCLEOTIDE'>FAS</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5hsa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hsa OCA], [http://pdbe.org/5hsa PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5hsa RCSB], [http://www.ebi.ac.uk/pdbsum/5hsa PDBsum]</span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5hsa FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5hsa OCA], [https://pdbe.org/5hsa PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5hsa RCSB], [https://www.ebi.ac.uk/pdbsum/5hsa PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5hsa ProSAT]</span></td></tr>
</table>
</table>
-
{{Large structure}}
 
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/ALOX1_KOMPC ALOX1_KOMPC]] Major isoform of alcohol oxidase, which catalyzes the oxidation of methanol to formaldehyde and hydrogen peroxide, the first step in the methanol utilization pathway of methylotrophic yeasts.<ref>PMID:2657390</ref> <ref>PMID:9396748</ref>
+
[https://www.uniprot.org/uniprot/ALOX1_KOMPC ALOX1_KOMPC] Major isoform of alcohol oxidase, which catalyzes the oxidation of methanol to formaldehyde and hydrogen peroxide, the first step in the methanol utilization pathway of methylotrophic yeasts.<ref>PMID:2657390</ref> <ref>PMID:9396748</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 24: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Alcohol oxidase]]
+
[[Category: Komagataella phaffii CBS 7435]]
-
[[Category: Feussner, I]]
+
[[Category: Large Structures]]
-
[[Category: Ficner, R]]
+
[[Category: Feussner I]]
-
[[Category: Koch, C]]
+
[[Category: Ficner R]]
-
[[Category: Neumann, P]]
+
[[Category: Koch C]]
-
[[Category: Oxidoreductase]]
+
[[Category: Neumann P]]

Current revision

Alcohol Oxidase AOX1 from Pichia Pastoris

PDB ID 5hsa

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools