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1rnf

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==X-RAY CRYSTAL STRUCTURE OF UNLIGANDED HUMAN RIBONUCLEASE 4==
==X-RAY CRYSTAL STRUCTURE OF UNLIGANDED HUMAN RIBONUCLEASE 4==
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<StructureSection load='1rnf' size='340' side='right' caption='[[1rnf]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='1rnf' size='340' side='right'caption='[[1rnf]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1rnf]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RNF OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1RNF FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1rnf]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1RNF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1RNF FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1rnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rnf OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1rnf RCSB], [http://www.ebi.ac.uk/pdbsum/1rnf PDBsum]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<table>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1rnf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1rnf OCA], [https://pdbe.org/1rnf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1rnf RCSB], [https://www.ebi.ac.uk/pdbsum/1rnf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1rnf ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/RNAS4_HUMAN RNAS4_HUMAN] This RNase has marked specificity towards the 3' side of uridine nucleotides.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rn/1rnf_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/rn/1rnf_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1rnf ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1rnf" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Ribonuclease|Ribonuclease]]
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*[[Ribonuclease 3D structures|Ribonuclease 3D structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Coll, M.]]
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[[Category: Large Structures]]
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[[Category: Gomis-Rueth, F X.]]
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[[Category: Coll M]]
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[[Category: Llorens, R De.]]
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[[Category: De Llorens R]]
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[[Category: Peracaula, R.]]
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[[Category: Gomis-Rueth FX]]
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[[Category: Seno, M.]]
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[[Category: Peracaula R]]
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[[Category: Terzyan, S S.]]
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[[Category: Seno M]]
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[[Category: Tsushima, Y.]]
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[[Category: Terzyan SS]]
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[[Category: Yamada, H.]]
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[[Category: Tsushima Y]]
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[[Category: Hydrolase]]
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[[Category: Yamada H]]
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[[Category: Phosphodiesterase]]
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[[Category: Ribonuclease]]
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Current revision

X-RAY CRYSTAL STRUCTURE OF UNLIGANDED HUMAN RIBONUCLEASE 4

PDB ID 1rnf

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