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1roz
From Proteopedia
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==Deoxyhypusine synthase holoenzyme in its low ionic strength, high pH crystal form== | ==Deoxyhypusine synthase holoenzyme in its low ionic strength, high pH crystal form== | ||
| - | <StructureSection load='1roz' size='340' side='right' caption='[[1roz]], [[Resolution|resolution]] 2.21Å' scene=''> | + | <StructureSection load='1roz' size='340' side='right'caption='[[1roz]], [[Resolution|resolution]] 2.21Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[1roz]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[1roz]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1ROZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1ROZ FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.21Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAD:NICOTINAMIDE-ADENINE-DINUCLEOTIDE'>NAD</scene></td></tr> | |
| - | <tr id=' | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1roz FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1roz OCA], [https://pdbe.org/1roz PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1roz RCSB], [https://www.ebi.ac.uk/pdbsum/1roz PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1roz ProSAT]</span></td></tr> |
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| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/DHYS_HUMAN DHYS_HUMAN] Catalyzes the NAD-dependent oxidative cleavage of spermidine and the subsequent transfer of the butylamine moiety of spermidine to the epsilon-amino group of a specific lysine residue of the eIF-5A precursor protein to form the intermediate deoxyhypusine residue. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ro/1roz_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ro/1roz_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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</div> | </div> | ||
<div class="pdbe-citations 1roz" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 1roz" style="background-color:#fffaf0;"></div> | ||
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| + | ==See Also== | ||
| + | *[[Deoxyhypusine synthase|Deoxyhypusine synthase]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Davies | + | [[Category: Davies DR]] |
| - | [[Category: Park | + | [[Category: Park M-H]] |
| - | [[Category: Umland | + | [[Category: Umland TC]] |
| - | [[Category: Wolff | + | [[Category: Wolff EC]] |
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Current revision
Deoxyhypusine synthase holoenzyme in its low ionic strength, high pH crystal form
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