This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1s97

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:14, 23 August 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='1s97' size='340' side='right'caption='[[1s97]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
<StructureSection load='1s97' size='340' side='right'caption='[[1s97]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1s97]] is a 12 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_35091 Atcc 35091]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S97 OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1S97 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1s97]] is a 12 chain structure with sequence from [https://en.wikipedia.org/wiki/Saccharolobus_solfataricus Saccharolobus solfataricus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1S97 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1S97 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DCT:2,3-DIDEOXYCYTIDINE+5-TRIPHOSPHATE'>DCT</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
-
<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">DBH, DPO4, SSO2448 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=2287 ATCC 35091])</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=DCT:2,3-DIDEOXYCYTIDINE+5-TRIPHOSPHATE'>DCT</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1s97 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s97 OCA], [https://pdbe.org/1s97 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1s97 RCSB], [https://www.ebi.ac.uk/pdbsum/1s97 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1s97 ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1s97 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1s97 OCA], [http://pdbe.org/1s97 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1s97 RCSB], [http://www.ebi.ac.uk/pdbsum/1s97 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1s97 ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/DPO4_SULSO DPO4_SULSO]] Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. It is involved in translesional synthesis.[HAMAP-Rule:MF_01113]
+
[https://www.uniprot.org/uniprot/DPO4_SACS2 DPO4_SACS2] Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. It is involved in translesional synthesis.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 37: Line 36:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Atcc 35091]]
 
-
[[Category: DNA-directed DNA polymerase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Aggarwal, A K]]
+
[[Category: Saccharolobus solfataricus]]
-
[[Category: Escalante, C R]]
+
[[Category: Aggarwal AK]]
-
[[Category: Johnson, R E]]
+
[[Category: Escalante CR]]
-
[[Category: Prakash, L]]
+
[[Category: Johnson RE]]
-
[[Category: Prakash, S]]
+
[[Category: Prakash L]]
-
[[Category: Trincao, J]]
+
[[Category: Prakash S]]
-
[[Category: Wolfle, W T]]
+
[[Category: Trincao J]]
-
[[Category: Dna duplex]]
+
[[Category: Wolfle WT]]
-
[[Category: G t mismatch]]
+
-
[[Category: Protein-dna complex]]
+
-
[[Category: Transferase-dna complex]]
+

Current revision

DPO4 with GT mismatch

PDB ID 1s97

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1s97"
Personal tools