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1sfj

From Proteopedia

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(New page: 200px<br /><applet load="1sfj" size="450" color="white" frame="true" align="right" spinBox="true" caption="1sfj, resolution 2.40&Aring;" /> '''2.4A Crystal structu...)
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[[Image:1sfj.gif|left|200px]]<br /><applet load="1sfj" size="450" color="white" frame="true" align="right" spinBox="true"
 
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caption="1sfj, resolution 2.40&Aring;" />
 
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'''2.4A Crystal structure of Staphylococcus aureus type I 3-dehydroquinase, with 3-dehydroquinate bound'''<br />
 
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==About this Structure==
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==2.4A Crystal structure of Staphylococcus aureus type I 3-dehydroquinase, with 3-dehydroquinate bound==
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1SFJ is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Staphylococcus_aureus Staphylococcus aureus] with DHK as [http://en.wikipedia.org/wiki/ligand ligand]. Active as [http://en.wikipedia.org/wiki/3-dehydroquinate_dehydratase 3-dehydroquinate dehydratase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.2.1.10 4.2.1.10] Full crystallographic information is available from [http://ispc.weizmann.ac.il/oca-bin/ocashort?id=1SFJ OCA].
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<StructureSection load='1sfj' size='340' side='right'caption='[[1sfj]], [[Resolution|resolution]] 2.40&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1sfj]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_MRSA252 Staphylococcus aureus subsp. aureus MRSA252]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SFJ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SFJ FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.4&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DHK:3-DEHYDROSHIKIMATE'>DHK</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sfj FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sfj OCA], [https://pdbe.org/1sfj PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sfj RCSB], [https://www.ebi.ac.uk/pdbsum/1sfj PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sfj ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/AROD_STAAR AROD_STAAR]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sf/1sfj_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sfj ConSurf].
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<div style="clear:both"></div>
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==Reference==
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==See Also==
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Crystal structures of Staphylococcus aureus type I dehydroquinase from enzyme turnover experiments., Nichols CE, Lockyer M, Hawkins AR, Stammers DK, Proteins. 2004 Aug 15;56(3):625-8. PMID:[http://ispc.weizmann.ac.il//pmbin/getpm?pmid=15229896 15229896]
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*[[Dehydroquinase 3D structures|Dehydroquinase 3D structures]]
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[[Category: 3-dehydroquinate dehydratase]]
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__TOC__
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[[Category: Single protein]]
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</StructureSection>
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[[Category: Staphylococcus aureus]]
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[[Category: Large Structures]]
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[[Category: Hawkins, A.R.]]
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[[Category: Staphylococcus aureus subsp. aureus MRSA252]]
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[[Category: Lockyer, M.]]
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[[Category: Hawkins AR]]
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[[Category: Nichols, C.E.]]
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[[Category: Lockyer M]]
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[[Category: Stammers, D.K.]]
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[[Category: Nichols CE]]
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[[Category: DHK]]
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[[Category: Stammers DK]]
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[[Category: 3-dehydroquinase]]
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[[Category: 3-dehydroquinate]]
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[[Category: enzyme turnover]]
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[[Category: shikimate pathway]]
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''Page seeded by [http://ispc.weizmann.ac.il/oca OCA ] on Wed Nov 21 02:21:00 2007''
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Current revision

2.4A Crystal structure of Staphylococcus aureus type I 3-dehydroquinase, with 3-dehydroquinate bound

PDB ID 1sfj

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