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1sh2

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==Crystal Structure of Norwalk Virus Polymerase (Metal-free, Centered Orthorhombic)==
==Crystal Structure of Norwalk Virus Polymerase (Metal-free, Centered Orthorhombic)==
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<StructureSection load='1sh2' size='340' side='right' caption='[[1sh2]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='1sh2' size='340' side='right'caption='[[1sh2]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1sh2]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Norwalk_virus Norwalk virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SH2 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SH2 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1sh2]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Norwalk_virus Norwalk virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SH2 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SH2 FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1khv|1khv]], [[1sh0|1sh0]], [[1sh3|1sh3]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/RNA-directed_RNA_polymerase RNA-directed RNA polymerase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.48 2.7.7.48] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sh2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sh2 OCA], [https://pdbe.org/1sh2 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sh2 RCSB], [https://www.ebi.ac.uk/pdbsum/1sh2 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sh2 ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sh2 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sh2 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1sh2 RCSB], [http://www.ebi.ac.uk/pdbsum/1sh2 PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q70ET3_9CALI Q70ET3_9CALI]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sh/1sh2_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sh/1sh2_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sh2 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1sh2" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[RNA polymerase|RNA polymerase]]
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*[[RNA polymerase 3D structures|RNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Norwalk virus]]
[[Category: Norwalk virus]]
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[[Category: RNA-directed RNA polymerase]]
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[[Category: Alonso JM]]
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[[Category: Alonso, J M.]]
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[[Category: Boga JA]]
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[[Category: Boga, J A.]]
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[[Category: Machin A]]
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[[Category: Machin, A.]]
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[[Category: Ng KK]]
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[[Category: Ng, K K.]]
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[[Category: Parra F]]
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[[Category: Parra, F.]]
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[[Category: Pendas-Franco N]]
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[[Category: Pendas-Franco, N.]]
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[[Category: Rojo J]]
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[[Category: Rojo, J.]]
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[[Category: Rna polymerase]]
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[[Category: Transferase]]
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[[Category: Viral enzyme]]
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[[Category: Viral replication]]
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Current revision

Crystal Structure of Norwalk Virus Polymerase (Metal-free, Centered Orthorhombic)

PDB ID 1sh2

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