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1sng

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==Structure of a Thermophilic Serpin in the Native State==
==Structure of a Thermophilic Serpin in the Native State==
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<StructureSection load='1sng' size='340' side='right' caption='[[1sng]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
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<StructureSection load='1sng' size='340' side='right'caption='[[1sng]], [[Resolution|resolution]] 1.76&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1sng]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermobifida_fusca Thermobifida fusca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SNG OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1SNG FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1sng]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermobifida_fusca Thermobifida fusca]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1SNG OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1SNG FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.76&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CAF:S-DIMETHYLARSINOYL-CYSTEINE'>CAF</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CAF:S-DIMETHYLARSINOYL-CYSTEINE'>CAF</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mtp|1mtp]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1sng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sng OCA], [https://pdbe.org/1sng PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1sng RCSB], [https://www.ebi.ac.uk/pdbsum/1sng PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1sng ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1sng FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1sng OCA], [http://www.rcsb.org/pdb/explore.do?structureId=1sng RCSB], [http://www.ebi.ac.uk/pdbsum/1sng PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q47NK3_THEFY Q47NK3_THEFY]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sn/1sng_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/sn/1sng_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1sng ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 1sng" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Serpin|Serpin]]
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*[[Serpin 3D structures|Serpin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Thermobifida fusca]]
[[Category: Thermobifida fusca]]
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[[Category: Bottomley, S P]]
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[[Category: Bottomley SP]]
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[[Category: Buckle, A M]]
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[[Category: Buckle AM]]
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[[Category: Butcher, R E]]
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[[Category: Butcher RE]]
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[[Category: Cabrita, L D]]
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[[Category: Cabrita LD]]
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[[Category: Fulton, K F]]
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[[Category: Fulton KF]]
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[[Category: Irving, J A]]
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[[Category: Irving JA]]
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[[Category: Lesk, A M]]
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[[Category: Lesk AM]]
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[[Category: Reeve, S]]
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[[Category: Reeve S]]
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[[Category: Rossjohn, J]]
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[[Category: Rossjohn J]]
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[[Category: Smith, I]]
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[[Category: Smith I]]
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[[Category: Whisstock, J C]]
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[[Category: Whisstock JC]]
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[[Category: Hydrolase inhibitor]]
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[[Category: Native state]]
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Current revision

Structure of a Thermophilic Serpin in the Native State

PDB ID 1sng

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