This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1u49

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (06:38, 23 August 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='1u49' size='340' side='right'caption='[[1u49]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
<StructureSection load='1u49' size='340' side='right'caption='[[1u49]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[1u49]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Atcc_12980 Atcc 12980]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U49 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U49 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[1u49]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Geobacillus_stearothermophilus Geobacillus stearothermophilus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U49 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U49 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
-
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=8OG:8-OXO-2-DEOXY-GUANOSINE-5-MONOPHOSPHATE'>8OG</scene></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=8OG:8-OXO-2-DEOXY-GUANOSINE-5-MONOPHOSPHATE'>8OG</scene>, <scene name='pdbligand=FRU:FRUCTOSE'>FRU</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=PRD_900003:sucrose'>PRD_900003</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1u45|1u45]], [[1u47|1u47]], [[1u48|1u48]], [[1u4b|1u4b]]</div></td></tr>
+
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/DNA-directed_DNA_polymerase DNA-directed DNA polymerase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.7.7 2.7.7.7] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u49 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u49 OCA], [https://pdbe.org/1u49 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u49 RCSB], [https://www.ebi.ac.uk/pdbsum/1u49 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u49 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u49 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u49 OCA], [https://pdbe.org/1u49 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u49 RCSB], [https://www.ebi.ac.uk/pdbsum/1u49 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u49 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
-
[[https://www.uniprot.org/uniprot/DPO1_GEOSE DPO1_GEOSE]] In addition to polymerase activity, this DNA polymerase exhibits 5' to 3' exonuclease activity.
+
[https://www.uniprot.org/uniprot/DPO1_GEOSE DPO1_GEOSE] In addition to polymerase activity, this DNA polymerase exhibits 5' to 3' exonuclease activity.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 31: Line 29:
</div>
</div>
<div class="pdbe-citations 1u49" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 1u49" style="background-color:#fffaf0;"></div>
 +
 +
==See Also==
 +
*[[DNA polymerase 3D structures|DNA polymerase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Atcc 12980]]
+
[[Category: Geobacillus stearothermophilus]]
-
[[Category: DNA-directed DNA polymerase]]
+
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Beese, L S]]
+
[[Category: Beese LS]]
-
[[Category: Carell, T]]
+
[[Category: Carell T]]
-
[[Category: Hsu, G W]]
+
[[Category: Hsu GW]]
-
[[Category: Ober, M]]
+
[[Category: Ober M]]
-
[[Category: Dna lesion]]
+
-
[[Category: Dna polymerase i]]
+
-
[[Category: Dna replication]]
+
-
[[Category: Klenow fragment]]
+
-
[[Category: Protein-dna complex]]
+
-
[[Category: Transferase-dna complex]]
+
-
[[Category: Translation replication]]
+

Current revision

Adenine-8oxoguanine mismatch at the polymerase active site

PDB ID 1u49

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1u49"
Personal tools