1u5v

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[[Image:1u5v.gif|left|200px]]<br /><applet load="1u5v" size="350" color="white" frame="true" align="right" spinBox="true"
 
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caption="1u5v, resolution 1.85&Aring;" />
 
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'''Structure of CitE complexed with triphosphate group of ATP form Mycobacterium tuberculosis'''<br />
 
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==About this Structure==
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==Structure of CitE complexed with triphosphate group of ATP form Mycobacterium tuberculosis==
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1U5V is a [http://en.wikipedia.org/wiki/Single_protein Single protein] structure of sequence from [http://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis] with <scene name='pdbligand=ATP:'>ATP</scene> and <scene name='pdbligand=FMT:'>FMT</scene> as [http://en.wikipedia.org/wiki/ligands ligands]. Active as [http://en.wikipedia.org/wiki/Citrate_(pro-3S)-lyase Citrate (pro-3S)-lyase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.3.6 4.1.3.6] Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U5V OCA].
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<StructureSection load='1u5v' size='340' side='right'caption='[[1u5v]], [[Resolution|resolution]] 1.85&Aring;' scene=''>
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[[Category: Citrate (pro-3S)-lyase]]
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1u5v]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis Mycobacterium tuberculosis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1U5V OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1U5V FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.85&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ATP:ADENOSINE-5-TRIPHOSPHATE'>ATP</scene>, <scene name='pdbligand=FMT:FORMIC+ACID'>FMT</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1u5v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1u5v OCA], [https://pdbe.org/1u5v PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1u5v RCSB], [https://www.ebi.ac.uk/pdbsum/1u5v PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1u5v ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CITEL_MYCTU CITEL_MYCTU] May play a role in fatty acid biosynthesis (Potential).
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/u5/1u5v_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1u5v ConSurf].
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<div style="clear:both"></div>
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__TOC__
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</StructureSection>
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[[Category: Large Structures]]
[[Category: Mycobacterium tuberculosis]]
[[Category: Mycobacterium tuberculosis]]
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[[Category: Single protein]]
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[[Category: Eisenberg E]]
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[[Category: Eisenberg, E.]]
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[[Category: Goulding CW]]
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[[Category: Goulding, C W.]]
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[[Category: Kim CY]]
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[[Category: Kim, C Y.]]
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[[Category: Lerkin T]]
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[[Category: Lerkin, T.]]
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[[Category: Segelke B]]
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[[Category: Segelke, B.]]
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[[Category: Terwilliger T]]
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[[Category: TBSGC, TB Structural Genomics Consortium.]]
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[[Category: Terwilliger, T.]]
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[[Category: ATP]]
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[[Category: FMT]]
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[[Category: protein structure initiative]]
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[[Category: psi]]
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[[Category: structural genomics]]
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[[Category: tb structural genomics consortium]]
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[[Category: tbsgc]]
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[[Category: tim-barrel]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Feb 21 15:20:52 2008''
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Current revision

Structure of CitE complexed with triphosphate group of ATP form Mycobacterium tuberculosis

PDB ID 1u5v

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