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1xgw

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Current revision (06:45, 23 August 2023) (edit) (undo)
 
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<StructureSection load='1xgw' size='340' side='right'caption='[[1xgw]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
<StructureSection load='1xgw' size='340' side='right'caption='[[1xgw]], [[Resolution|resolution]] 1.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1xgw]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XGW OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=1XGW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1xgw]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XGW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XGW FirstGlance]. <br>
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</td></tr><tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">EPN4, EPNR, ENTH, KIAA0171 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 HUMAN])</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=1xgw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xgw OCA], [http://pdbe.org/1xgw PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xgw RCSB], [http://www.ebi.ac.uk/pdbsum/1xgw PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1xgw ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xgw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xgw OCA], [https://pdbe.org/1xgw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xgw RCSB], [https://www.ebi.ac.uk/pdbsum/1xgw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xgw ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/EPN4_HUMAN EPN4_HUMAN]] Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly.<ref>PMID:12429846</ref> <ref>PMID:12538641</ref>
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[https://www.uniprot.org/uniprot/EPN4_HUMAN EPN4_HUMAN] Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2). May have a role in transport via clathrin-coated vesicles from the trans-Golgi network to endosomes. Stimulates clathrin assembly.<ref>PMID:12429846</ref> <ref>PMID:12538641</ref>
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Cygler, M]]
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[[Category: Cygler M]]
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[[Category: Lunin, V V]]
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[[Category: Lunin VV]]
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[[Category: Mazzoni, I]]
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[[Category: Mazzoni I]]
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[[Category: Munger, C]]
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[[Category: Munger C]]
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[[Category: Wagner, J]]
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[[Category: Wagner J]]
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[[Category: Clathrin-associated]]
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[[Category: Endocytosis]]
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[[Category: Enth]]
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[[Category: Enthoprotin]]
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[[Category: Epsin-related]]
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Current revision

The crystal structure of human enthoprotin N-terminal domain

PDB ID 1xgw

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