This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1xi3

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "1xi3" [edit=sysop:move=sysop])
Current revision (06:45, 23 August 2023) (edit) (undo)
 
(6 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:1xi3.png|left|200px]]
 
-
{{STRUCTURE_1xi3| PDB=1xi3 | SCENE= }}
+
==Thiamine phosphate pyrophosphorylase from Pyrococcus furiosus Pfu-1255191-001==
 +
<StructureSection load='1xi3' size='340' side='right'caption='[[1xi3]], [[Resolution|resolution]] 1.70&Aring;' scene=''>
 +
== Structural highlights ==
 +
<table><tr><td colspan='2'>[[1xi3]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XI3 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XI3 FirstGlance]. <br>
 +
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.7&#8491;</td></tr>
 +
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NI:NICKEL+(II)+ION'>NI</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=UNX:UNKNOWN+ATOM+OR+ION'>UNX</scene></td></tr>
 +
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xi3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xi3 OCA], [https://pdbe.org/1xi3 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xi3 RCSB], [https://www.ebi.ac.uk/pdbsum/1xi3 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xi3 ProSAT], [https://www.topsan.org/Proteins/SECSG/1xi3 TOPSAN]</span></td></tr>
 +
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/THIE_PYRFU THIE_PYRFU] Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP) (By similarity).
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xi/1xi3_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xi3 ConSurf].
 +
<div style="clear:both"></div>
-
===Thiamine phosphate pyrophosphorylase from Pyrococcus furiosus Pfu-1255191-001===
+
==See Also==
-
 
+
*[[Thiamin phosphate synthase|Thiamin phosphate synthase]]
-
 
+
__TOC__
-
==About this Structure==
+
</StructureSection>
-
[[1xi3]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Pyrococcus_furiosus Pyrococcus furiosus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XI3 OCA].
+
[[Category: Large Structures]]
-
[[Category: Pyrococcus furiosus]]
+
-
[[Category: Thiamine-phosphate diphosphorylase]]
+
-
[[Category: Adams, M W.W.]]
+
-
[[Category: Chang, S H.]]
+
-
[[Category: Chen, L.]]
+
-
[[Category: Dillard, B D.]]
+
-
[[Category: Eneh, J C.]]
+
-
[[Category: Habel, J.]]
+
-
[[Category: Hopkins, R C.]]
+
-
[[Category: II, F L.Poole.]]
+
-
[[Category: III, W B.Arendall.]]
+
-
[[Category: Jenney, F E.]]
+
-
[[Category: Kelley, L L.C.]]
+
-
[[Category: Lee, D.]]
+
-
[[Category: Lee, H S.]]
+
-
[[Category: Li, T.]]
+
-
[[Category: Lin, D.]]
+
-
[[Category: Liu, Z J.]]
+
-
[[Category: Richardson, D C.]]
+
-
[[Category: Richardson, J S.]]
+
-
[[Category: Rose, J P.]]
+
-
[[Category: SECSG, Southeast Collaboratory for Structural Genomics.]]
+
-
[[Category: Shah, C.]]
+
-
[[Category: Sugar, F J.]]
+
-
[[Category: Tempel, W.]]
+
-
[[Category: Wang, B C.]]
+
-
[[Category: Zhou, W.]]
+
-
[[Category: Hyperthermophile]]
+
-
[[Category: Protein structure initiative]]
+
-
[[Category: Psi]]
+
[[Category: Pyrococcus furiosus]]
[[Category: Pyrococcus furiosus]]
-
[[Category: Secsg]]
+
[[Category: Adams MWW]]
-
[[Category: Southeast collaboratory for structural genomic]]
+
[[Category: Arendall III WB]]
-
[[Category: Structural genomic]]
+
[[Category: Chang S-H]]
-
[[Category: Thiamine phosphate pyrophosphorylase]]
+
[[Category: Chen L]]
-
[[Category: Transferase]]
+
[[Category: Dillard BD]]
 +
[[Category: Eneh JC]]
 +
[[Category: Habel J]]
 +
[[Category: Hopkins RC]]
 +
[[Category: Jenney Jr FE]]
 +
[[Category: Kelley L-LC]]
 +
[[Category: Lee D]]
 +
[[Category: Lee H-S]]
 +
[[Category: Li T]]
 +
[[Category: Lin D]]
 +
[[Category: Liu Z-J]]
 +
[[Category: Poole II FL]]
 +
[[Category: Richardson DC]]
 +
[[Category: Richardson JS]]
 +
[[Category: Rose JP]]
 +
[[Category: Shah C]]
 +
[[Category: Sugar FJ]]
 +
[[Category: Tempel W]]
 +
[[Category: Wang B-C]]
 +
[[Category: Zhou W]]

Current revision

Thiamine phosphate pyrophosphorylase from Pyrococcus furiosus Pfu-1255191-001

PDB ID 1xi3

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1xi3"
Personal tools