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1xky

From Proteopedia

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[[Image:1xky.png|left|200px]]
 
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{{STRUCTURE_1xky| PDB=1xky | SCENE= }}
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==Crystal Structure of Dihydrodipicolinate Synthase DapA-2 (BA3935) from Bacillus Anthracis at 1.94A Resolution.==
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<StructureSection load='1xky' size='340' side='right'caption='[[1xky]], [[Resolution|resolution]] 1.94&Aring;' scene=''>
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===Crystal Structure of Dihydrodipicolinate Synthase DapA-2 (BA3935) from Bacillus Anthracis at 1.94A Resolution.===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[1xky]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKY OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XKY FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.94&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=K:POTASSIUM+ION'>K</scene></td></tr>
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[[1xky]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Bacillus_anthracis Bacillus anthracis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XKY OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xky FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xky OCA], [https://pdbe.org/1xky PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xky RCSB], [https://www.ebi.ac.uk/pdbsum/1xky PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xky ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/A0A6L7H340_BACAN A0A6L7H340_BACAN] Catalyzes the condensation of (S)-aspartate-beta-semialdehyde [(S)-ASA] and pyruvate to 4-hydroxy-tetrahydrodipicolinate (HTPA).[ARBA:ARBA00003294][HAMAP-Rule:MF_00418]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xk/1xky_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=1xky ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Dihydrodipicolinate Synthase|Dihydrodipicolinate Synthase]]
 
*[[Dihydrodipicolinate synthase|Dihydrodipicolinate synthase]]
*[[Dihydrodipicolinate synthase|Dihydrodipicolinate synthase]]
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__TOC__
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==Reference==
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</StructureSection>
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<ref group="xtra">PMID:016287120</ref><references group="xtra"/>
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[[Category: Bacillus anthracis]]
[[Category: Bacillus anthracis]]
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[[Category: Dihydrodipicolinate synthase]]
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[[Category: Large Structures]]
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[[Category: Blagova, E.]]
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[[Category: Blagova E]]
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[[Category: Brannigan, J A.]]
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[[Category: Brannigan JA]]
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[[Category: Fogg, M J.]]
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[[Category: Fogg MJ]]
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[[Category: Levdikov, V.]]
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[[Category: Levdikov V]]
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[[Category: Milioti, N.]]
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[[Category: Milioti N]]
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[[Category: Wilkinson, A J.]]
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[[Category: Wilkinson AJ]]
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[[Category: Wilson, K S.]]
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[[Category: Wilson KS]]
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[[Category: Crystal structure]]
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[[Category: Dihydrodipicolinate synthase]]
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[[Category: Lyase]]
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[[Category: Lysine biosynthesis]]
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[[Category: Spine]]
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[[Category: Tim barrel]]
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Current revision

Crystal Structure of Dihydrodipicolinate Synthase DapA-2 (BA3935) from Bacillus Anthracis at 1.94A Resolution.

PDB ID 1xky

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