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1xod

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==Crystal structure of X. tropicalis Spred1 EVH-1 domain==
==Crystal structure of X. tropicalis Spred1 EVH-1 domain==
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<StructureSection load='1xod' size='340' side='right' caption='[[1xod]], [[Resolution|resolution]] 1.15&Aring;' scene=''>
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<StructureSection load='1xod' size='340' side='right'caption='[[1xod]], [[Resolution|resolution]] 1.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[1xod]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Silurana_(xenopus)_tropicalis Silurana (xenopus) tropicalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XOD OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1XOD FirstGlance]. <br>
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<table><tr><td colspan='2'>[[1xod]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Xenopus_tropicalis Xenopus tropicalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1XOD OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=1XOD FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.15&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">Spred1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=8364 Silurana (Xenopus) tropicalis])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1xod FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xod OCA], [http://pdbe.org/1xod PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=1xod RCSB], [http://www.ebi.ac.uk/pdbsum/1xod PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=1xod ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=1xod FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1xod OCA], [https://pdbe.org/1xod PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=1xod RCSB], [https://www.ebi.ac.uk/pdbsum/1xod PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=1xod ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SPRE1_XENTR SPRE1_XENTR]] Tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase (By similarity).
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[https://www.uniprot.org/uniprot/SPRE1_XENTR SPRE1_XENTR] Tyrosine kinase substrate that inhibits growth-factor-mediated activation of MAP kinase (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Amaya, E]]
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[[Category: Large Structures]]
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[[Category: Blundell, T L]]
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[[Category: Xenopus tropicalis]]
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[[Category: Harmer, N J]]
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[[Category: Amaya E]]
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[[Category: Sivak, J M]]
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[[Category: Blundell TL]]
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[[Category: Evh1]]
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[[Category: Harmer NJ]]
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[[Category: Peptide-binding]]
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[[Category: Sivak JM]]
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[[Category: Signaling protein]]
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[[Category: Spred]]
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[[Category: Sprouty]]
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Current revision

Crystal structure of X. tropicalis Spred1 EVH-1 domain

PDB ID 1xod

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